SCHEMBL105934

SCHEMBL105934

C=CC(=O)OC[Si](C)(OCC)OCC

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.46
ALDH1A1 P00352 6/20 0.46
TP53 P04637 3/20 0.46
HIF1A Q16665 3/20 0.46
CYP3A4 P08684 2/20 0.46
MAPK1 P28482 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HPGD P15428 1/20 0.46
HSD17B10 Q99714 1/20 0.41
THRB P10828 3/20 0.39
HCAR2 Q8TDS4 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27853675 0.91 TSHR (0.42) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL27989549 0.87 TSHR (0.43) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL238722 0.85 TSHR (0.52) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL108961 0.85 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28717799 0.84 TSHR (0.56) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL3959259 0.84 HCAR2 (0.47) ALDH1A1HCAR2NPSR1
SCHEMBL109189 0.82 TSHR (0.47) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL5698947 0.82 TSHR (0.62) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1066175 0.81 TSHR (0.52) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL16537445 0.81 TSHR (0.43) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 363 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4035649-B1 DENTAL ADHESIVE COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-07-26 EP claimed
CN-115895353-A Preparation method of FEVE coating 江苏考普乐新材料股份有限公司 2023-04-04 CN claimed
EP-3328958-B1 USE OF A SINGLE OR MULTI COMPONENT SYSTEM FOR SECURING ANCHORING MEANS FISCHERWERKE GMBH & CO KG (DE) 2022-10-05 EP claimed
EP-4035649-A1 DENTAL ADHESIVE COMPOSITION 3M Innovative Properties Company (US) 2022-08-03 EP claimed
CN-108888316-B Antibacterial trouka 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 2021-05-14 CN claimed
EP-3328958-A2 USE OF A SINGLE OR MULTI COMPONENT SYSTEM FOR SECURING ANCHORING MEANS fischerwerke GmbH & Co. KG (DE) 2018-06-06 EP claimed
EP-3268411-A1 A POLYORGANOSILOXANE AND A MOISTURE AND RADIATION CURABLE ADHESIVE COMPOSITION COMPRISING THE SAME Henkel IP & Holding GmbH (DE) 2018-01-17 EP claimed
WO-2016141547-A1 A POLYORGANOSILOXANE AND A MOISTURE AND RADIATION CURABLE ADHESIVE COMPOSITION COMPRISING THE SAME Henkel IP Holding GmbH (DE) 2016-09-15 WO claimed
US-8865837-B2 Organosilicon compounds, production processes thereof, pressure-sensitive adhesive compositions containing the organosilicon compounds, self-adhesive polarizers and liquid crystal displays SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-10-21 US claimed
US-8865851-B2 Moisture-curing coating compositions comprising aprotic solvents and binders having alkoxysilane groups and method of forming a multicoat finish therewith BASF COATINGS GMBH (DE) 2014-10-21 US claimed
EP-2414466-B1 MOISTURE-CURING COATING COMPOSITIONS BASED ON APROTIC SOLVENTS, COMPRISING BINDERS HAVING ALKOXYSILANE GROUPS, AND THE USE THEREOF BASF COATINGS GMBH (DE) 2013-10-16 EP claimed
US-8431649-B2 Organosilicon compounds, production processes thereof, pressure-sensitive adhesive compositions containing the organosilicon compounds, self-adhesive polarizers and liquid crystal displays SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-04-30 US claimed
US-20120045586-A1 MOISTURE-CURING COATING COMPOSITIONS BASED ON APROTIC SOLVENTS COMPRISING BINDERS HAVING ALKOXYSILANE GROUPS AND THE USE THEREOF BASF COATINGS GMBH (DE) 2012-02-23 US claimed
EP-2414466-A1 MOISTURE-CURING COATING COMPOSITIONS BASED ON APROTIC SOLVENTS, COMPRISING BINDERS HAVING ALKOXYSILANE GROUPS, AND THE USE THEREOF BASF Coatings GmbH (DE) 2012-02-08 EP claimed
WO-2010112106-A1 MOISTURE-CURING COATING COMPOSITIONS BASED ON APROTIC SOLVENTS, COMPRISING BINDERS HAVING ALKOXYSILANE GROUPS, AND THE USE THEREOF BASF COATINGS AG (DE) 2010-10-07 WO claimed
US-6841694-B2 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2005-01-11 US claimed
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2004-09-02 US claimed
EP-4727982-A1 PRIMER COMPOSITION, ADHESIVE SYSTEM, AND RELATED PROCESSES 3M Innovative Properties Company (US) 2026-04-22 EP disclosed
US-5021266-A Silicon based protective coating SHIN-ETSU CHEMICAL CO., LTD. (JP) 1991-06-04 US disclosed
US-4960809-A CURABLE MIXTURE OF ALKOXYSILYL-CONTAINING ADDITION COPOLYMER AND AN AMIDATED POLYMER OF AN AMINE-CONTAINING ALKOXYSILANE AND SILYLATING AGENT; ADHESION TO SILICONE OVERCOATINGS AND POLYCARBONATE SUBSTRATE SHIN-ETSU CHEMICAL CO., LTD. (JP) 1990-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds ELOVL1, ELOVL6, DEGS1 TSHR 4650/4885ALDH1A1 402/4885TP53 4663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.