SCHEMBL229899

SCHEMBL229899

C=CC(=O)OC[Si](C)(OCCOC)OCCOC

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.42
ALDH1A1 P00352 4/20 0.42
TP53 P04637 3/20 0.42
HIF1A Q16665 3/20 0.42
CYP3A4 P08684 2/20 0.42
MAPK1 P28482 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HPGD P15428 1/20 0.42
HSD17B10 Q99714 1/20 0.41
THRB P10828 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL227221 0.86 TSHR (0.42) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL230526 0.84 TSHR (0.43) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL238722 0.84 TSHR (0.52) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL231020 0.82 TSHR (0.50) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL5698947 0.81 TSHR (0.62) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL105934 0.80 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL108692 0.80 TSHR (0.45) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL38483 0.77
SCHEMBL229906 0.76 ALDH1A1 (0.42) TSHRALDH1A1THRB
SCHEMBL27853675 0.76 TSHR (0.42) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2941460-B1 ONE -COMPONENT, CURABLE COATING COMPOSITION, PROCESSES FOR MAKING AND USING THEM, AND COATINGS AND ARTICLES PREPARED WITH THEM BASF COATINGS GMBH (DE) 2017-11-22 EP disclosed
US-9683125-B2 One-component, curable coating compositions, processes for making and using them, and coatings and articles prepared with them BASF COATINGS GMBH (DE) 2017-06-20 US disclosed
US-20150337159-A1 One-Component, Curable Coating Compositions, Processes For Making And Using Them, And Coatings And Articles Prepared With Them BASF COATINGS GMBH (DE) 2015-11-26 US disclosed
EP-2941460-A1 ONE -COMPONENT, CURABLE COATING COMPOSITION, PROCESSES FOR MAKING AND USING THEM, AND COATINGS AND ARTICLES PREPARED WITH THEM BASF Coatings GmbH (DE) 2015-11-11 EP disclosed
US-8865851-B2 Moisture-curing coating compositions comprising aprotic solvents and binders having alkoxysilane groups and method of forming a multicoat finish therewith BASF COATINGS GMBH (DE) 2014-10-21 US disclosed
WO-2014106552-A1 ONE -COMPONENT, CURABLE COATING COMPOSITION, PROCESSES FOR MAKING AND USING THEM, AND COATINGS AND ARTICLES PREPARED WITH THEM BASF COATINGS GMBH (DE) 2014-07-10 WO disclosed
EP-2414466-B1 MOISTURE-CURING COATING COMPOSITIONS BASED ON APROTIC SOLVENTS, COMPRISING BINDERS HAVING ALKOXYSILANE GROUPS, AND THE USE THEREOF BASF COATINGS GMBH (DE) 2013-10-16 EP disclosed
US-8247590-B2 Method for preventing polymerization of unsaturated organosilicon compounds WACKER CHEMIE AG (DE) 2012-08-21 US disclosed
EP-2334690-B1 METHOD FOR PRODUCING (METH)ACRYLOSILANES WACKER CHEMIE AG (DE) 2012-07-25 EP disclosed
EP-2300486-B1 METHOD FOR PREVENTING POLYMERIZATION OF UNSATURATED ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2012-03-28 EP disclosed
WO-2010112106-A1 MOISTURE-CURING COATING COMPOSITIONS BASED ON APROTIC SOLVENTS, COMPRISING BINDERS HAVING ALKOXYSILANE GROUPS, AND THE USE THEREOF BASF COATINGS AG (DE) 2010-10-07 WO disclosed
US-7619108-B2 Process for preparing unsaturated organosilicon compounds WACKER CHEMIE AG (DE) 2009-11-17 US disclosed
EP-1954701-B1 PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2009-03-18 EP disclosed
US-20080293958-A1 Process for Preparing Unsaturated Organosilicon Compounds WACKER CHEMIE AG (DE) 2008-11-27 US disclosed
US-6841694-B2 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2005-01-11 US disclosed
US-6815554-B2 REACTING A HALOALKYLSILANE WITH A SALT OF AN UNSATURATED CARBOXYLIC ACID IN THE PRESENCE OF A PHASE TRANSFER CATALYST; BONDING AGENTS WACKER-CHEMIE GMBH (DE) 2004-11-09 US disclosed
EP-1469002-A1 Method for stabilizing unsaturated organo-silicon compounds Wacker-Chemie GmbH (DE) 2004-10-20 EP disclosed
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2004-09-02 US disclosed
US-20020151736-A1 PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS WACKER-CHEMIE GMBH (DE) 2002-10-17 US disclosed
EP-1249454-A1 Preparation of unsaturated organo-silicon compounds Wacker-Chemie GmbH (DE) 2002-10-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds ELOVL1, ELOVL6, DEGS1 TSHR 4650/4885ALDH1A1 402/4885TP53 4663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.