Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | RXRG | P48443 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 5/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18833336 | 0.83 | RXRA (0.47) | RXRARXRBRXRGMRGPRX4PPARG | |
| SCHEMBL28060228 | 0.83 | RXRA (0.50) | RXRARXRBRXRGMRGPRX4PPARG | |
| SCHEMBL535975 | 0.81 | RXRA (0.49) | RXRARXRBRXRGMRGPRX4PPARG | |
| SCHEMBL21722981 | 0.81 | RXRA (0.49) | RXRARXRBRXRGMRGPRX4PPARG | |
| SCHEMBL31035275 | 0.81 | ALDH1A1 (0.50) | RXRARXRBRXRGMRGPRX4DRD2 | |
| SCHEMBL2095584 | 0.81 | RXRA (0.53) | RXRARXRBRXRGMRGPRX4PPARG | |
| SCHEMBL11840784 | 0.81 | RXRA (0.49) | RXRARXRBRXRGMRGPRX4PPARG | |
| SCHEMBL13253653 | 0.81 | CYP1A2 (0.51) | RXRARXRBRXRGDRD1 | |
| SCHEMBL6946500 | 0.81 | ALDH1A1 (0.50) | RXRARXRBRXRGMRGPRX4DRD2 | |
| SCHEMBL2095578 | 0.81 | RXRA (0.53) | RXRARXRBRXRGMRGPRX4PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675814-A1 | PHENOXYETHER DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-07-05 | — | — | EP | disclosed |
| WO-2005037763-A1 | PHENOXYETHER DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-04-28 | — | — | WO | disclosed |