SCHEMBL5698985

SCHEMBL5698985

OCC(O)c1ccc(OC(F)(F)F)cc1

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 6/20 0.49
PDE2A O00408 1/20 0.44
ALDH1A1 P00352 2/20 0.43
MAPT P10636 1/20 0.42
EPHX2 P34913 1/20 0.42
FAAH O00519 3/20 0.41
TRPV1 Q8NER1 3/20 0.41
MAOB P27338 1/20 0.39
AOC3 Q16853 1/20 0.39
TOP2A P11388 1/20 0.39
TOP2B Q02880 1/20 0.39
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5698984 1.00 SCN9A (0.49) SCN9APDE2AALDH1A1MAPTEPHX2
SCHEMBL16421367 0.83 FAAH (0.43) SCN9APDE2AALDH1A1MAPTEPHX2
SCHEMBL27999213 0.83 FAAH (0.43) SCN9APDE2AALDH1A1MAPTEPHX2
SCHEMBL16412790 0.83 FAAH (0.43) SCN9APDE2AALDH1A1MAPTEPHX2
SCHEMBL4542016 0.83 PDE2A (0.54) PDE2AALDH1A1MAPTMAOBAOC3
SCHEMBL6289310 0.83 TAAR1 (0.52) SCN9APDE2AALDH1A1MAPTFAAH
SCHEMBL12846690 0.81 PDE2A (0.41) SCN9APDE2AALDH1A1MAPTEPHX2
SCHEMBL9570810 0.81 PDE2A (0.44) SCN9APDE2AALDH1A1MAPTEPHX2
SCHEMBL9862495 0.81 PDE2A (0.44) SCN9APDE2AALDH1A1MAPTEPHX2
SCHEMBL16563938 0.80 PDE2A (0.44) PDE2AALDH1A1MAPTEPHX2FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1673463-A1 METHOD FOR TRANSFORMING EPOXY CARRIER OF TRIFLUOROMETHYL GROUPS Rhodia Chimie (FR) 2006-06-28 EP disclosed
WO-2005038036-A1 METHOD FOR TRANSFORMING EPOXY CARRIER OF TRIFLUOROMETHYL GROUPS RHODIA CHIMIE (FR) 2005-04-28 WO disclosed