Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.52 |
| ▸ | HTR3A | P46098 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | PNMT | P11086 | 1/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5698984 | 0.83 | SCN9A (0.49) | TSHRMAOBAOC3FAAHMAPT | |
| SCHEMBL5698985 | 0.83 | SCN9A (0.49) | TSHRMAOBAOC3FAAHMAPT | |
| SCHEMBL4542016 | 0.81 | PDE2A (0.54) | TSHRMAOBAOC3MAPTLMNA | |
| SCHEMBL16412790 | 0.81 | FAAH (0.43) | KDM4EMAOBAOC3SLC7A5FAAH | |
| SCHEMBL16421367 | 0.81 | FAAH (0.43) | KDM4EMAOBAOC3SLC7A5FAAH | |
| SCHEMBL27999213 | 0.81 | FAAH (0.43) | KDM4EMAOBAOC3SLC7A5FAAH | |
| SCHEMBL12846690 | 0.80 | PDE2A (0.41) | MAOBAOC3SLC7A5FAAHMAPT | |
| SCHEMBL12895269 | 0.80 | L3MBTL1 (0.47) | PDE2ASCN9AALDH1A1SLC6A4 | |
| SCHEMBL3405700 | 0.80 | PNMT (0.59) | AOC3PNMTFAAHSCN9A | |
| SCHEMBL28447540 | 0.79 | SLC7A5 (0.44) | TSHRMAOBAOC3SLC7A5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2005330229-A | 4-TRIFLUOROMETHOXYPHENYL(OXY)ETHYLAMINE DERIVATIVE AND ANTIMICROBIAL AGENT | UBE IND LTD | 2005-12-02 | — | — | JP | disclosed |