SCHEMBL5698987

SCHEMBL5698987

CCOC(=O)n1cncc1C[C@H](N)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 1/20 0.44
GRIA1 P42261 4/20 0.43
GRIA3 P42263 4/20 0.43
GRIA2 P42262 3/20 0.43
GRIA4 P48058 3/20 0.43
NOS1 P29475 3/20 0.40
CYP3A4 P08684 3/20 0.39
SLC7A5 Q01650 2/20 0.39
CYP1A2 P05177 2/20 0.37
GABRA1 P14867 2/20 0.37
GABRB2 P47870 2/20 0.37
CYP11B1 P15538 2/20 0.37
CYP11B2 P19099 2/20 0.37
CYP2C9 P11712 2/20 0.37
CYP2C19 P33261 2/20 0.37
LMNA P02545 1/20 0.37
ABCB11 O95342 1/20 0.37
GABRA2 P47869 1/20 0.37
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7300346 0.83 SLC7A5 (0.47) SLC1A3GRIA2NOS1SLC7A5
SCHEMBL3684988 0.82 SLC1A3 (0.49) SLC1A3GRIA1GRIA3GRIA2GRIA4
SCHEMBL5283559 0.81 SLC1A3 (0.48) SLC1A3GRIA1GRIA3GRIA2GRIA4
SCHEMBL5283564 0.81 SLC1A3 (0.48) SLC1A3GRIA1GRIA3GRIA2GRIA4
SCHEMBL22443734 0.81 SLC1A3 (0.48) SLC1A3GRIA1GRIA3GRIA2GRIA4
SCHEMBL5795113 0.77 SLC1A3 (0.49) SLC1A3GRIA1GRIA3GRIA2GRIA4
SCHEMBL8932777 0.77 SLC1A3 (0.49) SLC1A3GRIA1GRIA3GRIA2GRIA4
SCHEMBL8824879 0.76 SLC1A3 (0.51) SLC1A3GRIA1GRIA3GRIA2GRIA4
SCHEMBL8824882 0.76 SLC1A3 (0.51) SLC1A3GRIA1GRIA3GRIA2GRIA4
SCHEMBL28560 0.76 SLC1A3 (0.51) SLC1A3GRIA1GRIA3GRIA2GRIA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1689785-A2 USE OF METALLIC CATIONS TO IMPROVE FUNCTIONAL ACTIVITY OF ANTIBODIES Laboratoire Français du Fractionnement et des Biotechnologies (FR) 2006-08-16 EP disclosed
WO-2005040216-A2 USE OF METALLIC CATIONS TO IMPROVE FUNCTIONAL ACTIVITY OF ANTIBODIES LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES BIOTECHNOLOGIES (FR) 2005-05-06 WO disclosed