Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.51 |
| ▸ | GRIA4 | P48058 | 6/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 6/20 | 0.45 |
| ▸ | GRIA3 | P42263 | 6/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28560 | 1.00 | SLC1A3 (0.51) | SLC1A3GRIA4GRIA1GRIA3GRIA2 | |
| SCHEMBL28559 | 1.00 | SLC1A3 (0.51) | SLC1A3GRIA4GRIA1GRIA3GRIA2 | |
| SCHEMBL8824882 | 1.00 | SLC1A3 (0.51) | SLC1A3GRIA4GRIA1GRIA3GRIA2 | |
| SCHEMBL4587261 | 1.00 | SLC1A3 (0.51) | SLC1A3GRIA4GRIA1GRIA3GRIA2 | |
| Hydrochloric Acid SCHEMBL7049998 | 0.98 | SLC1A3 (0.50) | SLC1A3GRIA4GRIA1GRIA3GRIA2 | |
| SCHEMBL12610414 | 0.91 | SLC1A3 (0.44) | SLC1A3GRIA4GRIA1GRIA3GRIA2 | |
| SCHEMBL12610410 | 0.91 | SLC1A3 (0.44) | SLC1A3GRIA4GRIA1GRIA3GRIA2 | |
| Homoserine SCHEMBL28894150 | 0.91 | NOS1 (0.45) | SLC1A3GRIA4GRIA1GRIA3GRIA2 | |
| Sarcosine SCHEMBL16540745 | 0.89 | SLC1A3 (0.43) | SLC1A3GRIA4GRIA1GRIA3GRIA2 | |
| SCHEMBL15210329 | 0.89 | SLC1A3 (0.43) | SLC1A3GRIA4GRIA1GRIA3GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5628328-A | ADMINISTERING A METABOLIC MARKER FOR 3-METHYLHISTIDINE TO A HUMAN, PERIODICALLY REMOVING BLOOD OR URINE SAMPLES FROM SUBJECT, MEASURING MARKER IN EACH SAMPLE, GENERATING A MATHEMATICAL MODEL FROM MEASUREMENTS AND CALCULATING MASS | IOWA STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1997-05-13 | — | — | US | disclosed |