Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 5/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 3/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11463027 | 0.86 | DPP4 (0.40) | SLC15A1FNTAFNTBPGGT1BMEN1 | |
| SCHEMBL5698987 | 0.83 | SLC1A3 (0.44) | SLC7A5NOS1SLC1A3GRIA2 | |
| SCHEMBL2512335 | 0.81 | SLC7A5 (0.50) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL2507563 | 0.81 | SLC7A5 (0.50) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL2503926 | 0.81 | SLC7A5 (0.50) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL6554133 | 0.79 | CYP11B1 (0.46) | FNTAFNTBPGGT1BMEN1KMT2A | |
| SCHEMBL5171581 | 0.78 | SLC7A5 (0.47) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL18814657 | 0.78 | SMN1; SMN2 (0.40) | — | |
| Phenylalanine SCHEMBL11781896 | 0.76 | SLC7A5 (0.54) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL22784007 | 0.76 | ALDH1A1 (0.45) | SLC15A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0473936-A1 | Renin Inhibitors | AMERICAN CYANAMID COMPANY (US) | 1992-03-11 | — | — | EP | disclosed |