SCHEMBL5699017

SCHEMBL5699017

C=CC(=O)O[Si](C(C)C)(C(C)C)C(C)(C)C(C)C

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5699096 0.87 TSHR (0.35) TSHR
SCHEMBL5699038 0.85 TSHR (0.39) TSHR
SCHEMBL5699020 0.83 TSHR (0.37) TSHR
SCHEMBL5698992 0.83 TSHR (0.37) TSHR
SCHEMBL5699060 0.80 TSHR (0.35) TSHR
SCHEMBL15825254 0.79 TSHR (0.38) TSHR
SCHEMBL5699056 0.79 TSHR (0.39) TSHR
SCHEMBL7568811 0.76 TSHR (0.37) TSHR
SCHEMBL7574153 0.76 TSHR (0.41) TSHR
SCHEMBL2184768 0.76 TSHR (0.38) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1238980-B1 Silyl (meth)acrylates having bulky substituent group and preparation thereof SHINETSU CHEMICAL CO (JP) 2006-06-14 EP claimed
US-6498264-B2 REACTING A CHLOROSILANE COMPOUND WITH ACRYLIC OR METHACRYLIC ACID IN THE PRESENCE OF A BASIC COMPOUND; PROTECTIVE HYDROLYSABLE COATINGS FOR SHIP BOTTOMS; NONTOXIC; POLLUTION CONTROL; KINETICS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-12-24 US claimed
US-20020128503-A1 Silyl (meth)acrylates having bulky substituent group and preparation thereof SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-09-12 US claimed
EP-1238980-A1 Silyl (meth)acrylates having bulky substituent group and preparation thereof SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-09-11 EP claimed
EP-1238980-B1 Silyl (meth)acrylates having bulky substituent group and preparation thereof SHINETSU CHEMICAL CO (JP) 2006-06-14 EP disclosed
US-6498264-B2 REACTING A CHLOROSILANE COMPOUND WITH ACRYLIC OR METHACRYLIC ACID IN THE PRESENCE OF A BASIC COMPOUND; PROTECTIVE HYDROLYSABLE COATINGS FOR SHIP BOTTOMS; NONTOXIC; POLLUTION CONTROL; KINETICS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-12-24 US disclosed
US-20020128503-A1 Silyl (meth)acrylates having bulky substituent group and preparation thereof SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-09-12 US disclosed
EP-1238980-A1 Silyl (meth)acrylates having bulky substituent group and preparation thereof SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-09-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020128503-A1 Silyl (meth)acrylates having bulky substituent group and preparation thereof SMS, MASTL, ACR TSHR 4007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.