Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | F2R | P25116 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | DHODH | Q02127 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6653250 | 0.82 | MEN1 (0.35) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL6647935 | 0.72 | NPSR1 (0.37) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL8625558 | 0.71 | KMT2A (0.40) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL6651194 | 0.70 | MAPT (0.39) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL5733644 | 0.70 | KMT2A (0.34) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL7844242 | 0.68 | MEN1 (0.40) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL8645991 | 0.68 | MEN1 (0.41) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL25069399 | 0.67 | NPSR1 (0.40) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL2904253 | 0.67 | MAPT (0.34) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL5204690 | 0.67 | MAPT (0.34) | MEN1KMT2AMAPTLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362843-B1 | N-cyclopropyl-2-difluoromethoxy-3-bromoaniline and intermediate used for production thereof | IHARA CHEMICAL IND CO (JP) | 2006-06-14 | — | — | EP | disclosed |
| EP-1031555-B1 | DIFLUOROMETHOXYBENZENE DERIVATIVES AND THEIR USE AS INTERMEDIATES | IHARA CHEMICAL IND CO (JP) | 2005-04-13 | — | — | EP | disclosed |
| EP-1362843-A2 | N-cyclopropyl-2-difluoromethoxy-3-halogenoaniline and intermediate used for production thereof | Ihara Chemical Industry Co., Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-6316658-B1 | QUINOLONE CARBOXYLATE CHEMICAL INTERMEDIATES; MICROBIOCIDES, BACTERICIDES | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2001-11-13 | — | — | US | disclosed |
| EP-1031555-A1 | N-CYCLOPROPYL-2-DIFLUOROMETHOXY-3-HALOGENOANILINES AND INTERMEDIATES FOR THE PREPARATION THEREOF | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2000-08-30 | — | — | EP | disclosed |