Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6647935 | 0.88 | NPSR1 (0.37) | MEN1KMT2ANPSR1LMNAMAPT | |
| SCHEMBL8625558 | 0.86 | KMT2A (0.40) | MEN1KMT2ANPSR1LMNAMAPT | |
| SCHEMBL6651194 | 0.85 | MAPT (0.39) | MEN1KMT2ANPSR1LMNAMAPT | |
| SCHEMBL5699159 | 0.82 | MEN1 (0.34) | MEN1KMT2ANPSR1LMNAMAPT | |
| SCHEMBL8645991 | 0.75 | MEN1 (0.41) | MEN1KMT2ANPSR1LMNAMAPT | |
| SCHEMBL25069399 | 0.75 | NPSR1 (0.40) | MEN1KMT2ANPSR1LMNAMAPT | |
| SCHEMBL8626320 | 0.73 | ALDH1A1 (0.40) | MEN1KMT2ANPSR1LMNAMAPT | |
| SCHEMBL262000 | 0.71 | MAPT (0.38) | MEN1KMT2ANPSR1LMNAMAPT | |
| SCHEMBL27345346 | 0.71 | MAPT (0.41) | MEN1KMT2ANPSR1LMNAMAPT | |
| SCHEMBL10656978 | 0.69 | KMT2A (0.42) | MEN1KMT2ANPSR1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990639-B1 | PROCESS FOR PRODUCING N-CYCLOPROPYLANILINES AND INTERMEDIATES USED THEREFOR | IHARA CHEMICAL IND CO (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6162944-A | Process for production of N-cyclopropylanilines and intermediates therefor | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2000-12-19 | — | — | US | disclosed |
| EP-0990639-A1 | PROCESS FOR PRODUCING N-CYCLOPROPYLANILINES AND INTERMEDIATES USED THEREFOR | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2000-04-05 | — | — | EP | disclosed |