Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | S100A4 | P26447 | 2/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29134271 | 0.87 | HSPB1 (0.39) | TDP1HSPB1GPR35NPC1RECQL | |
| SCHEMBL15283229 | 0.83 | TDP1 (0.44) | TDP1HSPB1GPR35NPC1RECQL | |
| SCHEMBL26162786 | 0.80 | TDP1 (0.39) | TDP1HSPB1GPR35NPC1RECQL | |
| SCHEMBL7124190 | 0.80 | MAPT (0.47) | TDP1HSPB1GPR35NPC1RECQL | |
| SCHEMBL7125229 | 0.80 | TDP1 (0.41) | TDP1HSPB1GPR35NPC1RECQL | |
| SCHEMBL28837910 | 0.78 | CYP1A2 (0.43) | TDP1GPR35NPC1RAB9AALDH1A1 | |
| SCHEMBL28837911 | 0.78 | CYP1A2 (0.43) | TDP1GPR35NPC1RAB9AALDH1A1 | |
| SCHEMBL1771083 | 0.78 | MEN1 (0.36) | MEN1ALOX15KMT2A | |
| SCHEMBL31226691 | 0.78 | ALDH1A1 (0.41) | TDP1HSPB1GPR35NPC1RECQL | |
| SCHEMBL30778343 | 0.78 | ALDH1A1 (0.40) | TDP1ALDH1A1TSHRMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12637435-B2 | Nitrogen-containing heterocyclic compound or salt thereof, use thereof, and intermediate thereof | FUJIFILM CORPORATION (JP) | 2026-05-26 | — | — | US | disclosed |
| US-12421217-B2 | Pyrazine derivative or salt thereof, and use of same | FUJIFILM CORPORATION (JP) | 2025-09-23 | — | — | US | disclosed |
| EP-4190402-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND OR SALT THEREOF, USE THEREOF, AND INTERMEDIATE THEREOF | FUJIFILM CORP (JP) | 2025-08-27 | — | — | EP | disclosed |
| US-20250163004-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY | 2025-05-22 | — | — | US | disclosed |
| US-20240190829-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY | 2024-06-13 | — | — | US | disclosed |
| CN-117794912-A | Substituted heterocyclic compounds | 百时美施贵宝公司 | 2024-03-29 | — | — | CN | disclosed |
| US-20240101548-A1 | HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | SHENZHEN CHIPSCREEN BIOSCIENCES CO., LTD (CN) | 2024-03-28 | — | — | US | disclosed |
| EP-4337655-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS | Bristol-Myers Squibb Company (US) | 2024-03-20 | — | — | EP | disclosed |
| EP-4052760-B1 | PYRAZINE DERIVATIVE OR SALT THEREOF, AND USE OF SAME | FUJIFILM CORP (JP) | 2024-03-13 | — | — | EP | disclosed |
| US-11866414-B2 | Substituted heterocyclic compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-01-09 | — | — | US | disclosed |
| US-20220259185-A1 | PYRAZINE DERIVATIVE OR SALT THEREOF, AND USE OF SAME | FUJIFILM CORPORATION (JP) | 2022-08-18 | — | — | US | disclosed |
| CN-114901656-A | Hydroximic acid ester compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2022-08-12 | — | — | CN | disclosed |
| WO-2022117016-A1 | HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 深圳微芯生物科技股份有限公司 | 2022-06-09 | — | — | WO | disclosed |
| WO-2022025174-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND OR SALT THEREOF, USE THEREOF, AND INTERMEDIATE THEREOF | 富士フイルム株式会社 | 2022-02-03 | — | — | WO | disclosed |
| WO-2021085582-A1 | PYRAZINE DERIVATIVE OR SALT THEREOF, AND USE OF SAME | 富士フイルム株式会社 | 2021-05-06 | — | — | WO | disclosed |
| EP-1362843-B1 | N-cyclopropyl-2-difluoromethoxy-3-bromoaniline and intermediate used for production thereof | IHARA CHEMICAL IND CO (JP) | 2006-06-14 | — | — | EP | disclosed |
| EP-1031555-B1 | DIFLUOROMETHOXYBENZENE DERIVATIVES AND THEIR USE AS INTERMEDIATES | IHARA CHEMICAL IND CO (JP) | 2005-04-13 | — | — | EP | disclosed |
| EP-1362843-A2 | N-cyclopropyl-2-difluoromethoxy-3-halogenoaniline and intermediate used for production thereof | Ihara Chemical Industry Co., Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-6316658-B1 | QUINOLONE CARBOXYLATE CHEMICAL INTERMEDIATES; MICROBIOCIDES, BACTERICIDES | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2001-11-13 | — | — | US | disclosed |
| EP-1031555-A1 | N-CYCLOPROPYL-2-DIFLUOROMETHOXY-3-HALOGENOANILINES AND INTERMEDIATES FOR THE PREPARATION THEREOF | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2000-08-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240101548-A1 | HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | TYK2, WEE2, WEE1 | TDP1 1205/4885HSPB1 2825/4885GPR35 1916/4885 |
| US-11866414-B2 | Substituted heterocyclic compounds | TYK2, JAK2, STAT3 | TDP1 455/4885HSPB1 4123/4885GPR35 994/4885 |
| US-20250163004-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS | TYK2, JAK2, STAT3 | TDP1 455/4885HSPB1 4123/4885GPR35 994/4885 |
| US-12421217-B2 | Pyrazine derivative or salt thereof, and use of same | DHODH, IDH1, IDH2 | TDP1 1422/4885HSPB1 3161/4885GPR35 3104/4885 |
| US-12637435-B2 | Nitrogen-containing heterocyclic compound or salt thereof, use thereof, and intermediate thereof | CBR1, DHODH, CBR3 | TDP1 2604/4885HSPB1 3854/4885GPR35 3504/4885 |
| US-20240190829-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS | TYK2, JAK2, STAT3 | TDP1 455/4885HSPB1 4123/4885GPR35 994/4885 |
| US-20220259185-A1 | PYRAZINE DERIVATIVE OR SALT THEREOF, AND USE OF SAME | DHODH, IDH1, IDH2 | TDP1 1422/4885HSPB1 3161/4885GPR35 3104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.