Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | TTK | P33981 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | QPCT | Q16769 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL569240 | 0.85 | MCHR1 (0.45) | TTKMEN1KMT2AMAPTMCHR1 | |
| SCHEMBL569399 | 0.84 | TTK (0.39) | KITTTKLRRK2MEN1KMT2A | |
| SCHEMBL569973 | 0.84 | CHEK1 (0.38) | KITTTKLRRK2MCHR1 | |
| SCHEMBL569267 | 0.84 | MAPT (0.42) | MEN1KMT2AMAPTHPGDTP53 | |
| SCHEMBL569395 | 0.83 | ALDH1A1 (0.38) | KITTTKLRRK2MEN1KMT2A | |
| SCHEMBL569785 | 0.82 | HDAC8 (0.42) | MEN1KMT2AMAPTMCHR1ALDH1A1 | |
| SCHEMBL569244 | 0.82 | MAPT (0.43) | MEN1KMT2AMAPTHPGDTP53 | |
| SCHEMBL570137 | 0.80 | BACE1 (0.40) | KITLRRK2MEN1KMT2AMAPT | |
| SCHEMBL10182581 | 0.79 | PLA2G10 (0.46) | LRRK2MEN1KMT2AMAPTHPGD | |
| SCHEMBL569928 | 0.78 | LRRK2 (0.38) | LRRK2MEN1KMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601208-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | Graffinity Pharmaceuticals GmbH (DE) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012017021-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-09 | — | — | WO | disclosed |