Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | CFTR | P13569 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL569396 | 0.82 | ALDH1A1 (0.38) | LRRK2PDE5AHDAC11HDAC8MAPT | |
| SCHEMBL569786 | 0.81 | HCAR2 (0.48) | HDAC8MAPTMEN1KMT2AHPGD | |
| SCHEMBL569245 | 0.81 | KMT2A (0.41) | MAPTMEN1KMT2AHPGDKDM4E | |
| SCHEMBL569400 | 0.81 | HTT (0.38) | LRRK2PDE5AHDAC11HDAC8MAPT | |
| SCHEMBL569927 | 0.78 | KIT (0.36) | LRRK2MAPTMEN1KMT2AHPGD | |
| SCHEMBL10182581 | 0.76 | PLA2G10 (0.46) | LRRK2MAPTMEN1KMT2AHPGD | |
| SCHEMBL569756 | 0.74 | DRD3 (0.54) | MAPTMEN1KMT2AHPGDKDM4E | |
| SCHEMBL569408 | 0.74 | MAPT (0.42) | MAPTMEN1KMT2AHPGDKDM4E | |
| SCHEMBL10182349 | 0.73 | CFTR (0.43) | LRRK2MAPTMEN1KMT2AHPGD | |
| SCHEMBL10083554 | 0.72 | KMT2A (0.44) | LRRK2MAPTKMT2AMCHR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601208-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | Graffinity Pharmaceuticals GmbH (DE) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012017021-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-09 | — | — | WO | disclosed |