Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | ESR1 | P03372 | 2/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.57 |
| ▸ | TACR2 | P21452 | 2/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | SHBG | P04278 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | TST | Q16762 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5699267 | 1.00 | ALDH1A1 (0.57) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL27541801 | 0.94 | S1PR2 (0.55) | ALDH1A1HSD17B10S1PR2S1PR1S1PR3 | |
| SCHEMBL5699344 | 0.92 | ESR1 (0.49) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL6544811 | 0.91 | ALDH1A1 (0.62) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL27912642 | 0.90 | CNR1 (0.52) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL1716640 | 0.88 | MMP2 (0.55) | S1PR2S1PR1MMP2MMP3GRIK1 | |
| SCHEMBL8905851 | 0.88 | MMP2 (0.55) | S1PR2S1PR1MMP2MMP3GRIK1 | |
| SCHEMBL7077500 | 0.88 | MMP2 (0.55) | S1PR2S1PR1MMP2MMP3GRIK1 | |
| SCHEMBL8905261 | 0.88 | MMP2 (0.55) | S1PR2S1PR1MMP2MMP3GRIK1 | |
| SCHEMBL28210404 | 0.88 | MMP2 (0.55) | S1PR2S1PR1MMP2MMP3GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516866-B1 | NATURAL COMPOUNDS AND DERIVATIVES THEREOF FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR, HEPATIC AND RENAL DISEASES AND FOR COSMETIC APPLICATIONS | PULEVA BIOTECH SA (ES) | 2006-07-12 | — | — | EP | claimed |