Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 11/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4816225 | 1.00 | ADRB3 (0.40) | ADRB3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4820454 | 0.96 | ADRB3 (0.39) | ADRB3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4820449 | 0.96 | ADRB3 (0.39) | ADRB3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5699440 | 0.90 | KEAP1 (0.39) | ADRB3FFAR1 | |
| SCHEMBL5699447 | 0.90 | KEAP1 (0.39) | ADRB3FFAR1 | |
| SCHEMBL4818984 | 0.89 | ADRB3 (0.42) | ADRB3FFAR1 | |
| SCHEMBL5699461 | 0.89 | FFAR1 (0.47) | ADRB3FFAR1 | |
| SCHEMBL4815105 | 0.89 | ADRB3 (0.39) | ADRB3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5699460 | 0.89 | FFAR1 (0.47) | ADRB3FFAR1 | |
| SCHEMBL4815109 | 0.89 | ADRB3 (0.39) | ADRB3PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417169-B2 | Amino alcohol derivatives, medicinal composition containing the same, and use of these | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-08-26 | — | — | US | disclosed |
| US-20070078184-A1 | Amino alcohol derivatives, medicinal composition containing the same, and use of these | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078184-A1 | Amino alcohol derivatives, medicinal composition containing the same, and use of these | ADRB2, ADRA2A, ADRA1A | ADRB3 5/4885PDE4A 597/4885PDE4B 585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.