Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 4/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5699338 | 0.96 | ADRA1A (0.38) | ADRA1AADRA1DADRA1BL3MBTL1KDM4E | |
| SCHEMBL5699430 | 0.93 | MRGPRX4 (0.38) | ADRA1AADRA1DADRA1BL3MBTL1KDM4E | |
| SCHEMBL5699514 | 0.90 | ADRA1D (0.39) | ADRA1AADRA1DADRA1BL3MBTL1KDM4E | |
| SCHEMBL5699370 | 0.88 | FFAR1 (0.38) | ADRA1AADRA1DADRA1BADRB1ADRB3 | |
| SCHEMBL5699492 | 0.86 | MCL1 (0.40) | ADRA1AADRA1DADRA1BHTR1AADRB1 | |
| SCHEMBL5699495 | 0.85 | ADRA1D (0.41) | ADRA1AADRA1DADRA1BL3MBTL1KDM4E | |
| SCHEMBL5699513 | 0.84 | FFAR1 (0.39) | ADRA1AADRA1DADRA1BMRGPRX4HTR1A | |
| SCHEMBL4815105 | 0.83 | ADRB3 (0.39) | L3MBTL1ADRB1PDE4DCYP19A1ADRB3 | |
| SCHEMBL4815109 | 0.83 | ADRB3 (0.39) | L3MBTL1ADRB1PDE4DCYP19A1ADRB3 | |
| SCHEMBL5699446 | 0.83 | ADRA1D (0.39) | ADRA1AADRA1DADRA1BKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1679304-A1 | AMINO ALCOHOL DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USE OF THESE | Kissei Pharmaceutical Co., Ltd. (JP) | 2006-07-12 | — | — | EP | disclosed |