Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL27573797 | 0.98 | DAO (0.48) | DAOTSHRNAPRTALDH1A1LMNA | |
| Benzoic Acid SCHEMBL560461 | 0.91 | TSHR (0.56) | DAOTSHRNAPRTALDH1A1LMNA | |
| Benzoic Acid SCHEMBL28993296 | 0.91 | TSHR (0.56) | DAOTSHRNAPRTALDH1A1LMNA | |
| Benzoic Acid SCHEMBL17594839 | 0.87 | TSHR (0.61) | DAOTSHRNAPRTALDH1A1LMNA | |
| Benzoic Acid SCHEMBL560829 | 0.87 | TSHR (0.61) | DAOTSHRNAPRTALDH1A1LMNA | |
| Benzoic Acid SCHEMBL4577010 | 0.87 | TSHR (0.61) | DAOTSHRNAPRTALDH1A1LMNA | |
| Benzoic Acid SCHEMBL1073214 | 0.87 | TSHR (0.61) | DAOTSHRNAPRTALDH1A1LMNA | |
| Benzoic Acid SCHEMBL1068956 | 0.87 | TSHR (0.61) | DAOTSHRNAPRTALDH1A1LMNA | |
| Benzoic Acid SCHEMBL561248 | 0.86 | DAO (0.47) | DAOTSHRNAPRTALDH1A1LMNA | |
| Benzoic Acid SCHEMBL15136032 | 0.86 | DAO (0.47) | DAOTSHRNAPRTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478846-A | Carrier of catalyst with function of catalyzing olefin polymerization, preparation method and application of carrier, olefin polymerization catalyst and application of olefin polymerization catalyst | 中国石油化工股份有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-114085301-B | Solid catalyst component for preparing olefin polymer and application thereof | 中国石油化工股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| EP-3397658-B1 | NON-PHTHALATE CATALYST SYSTEM AND ITS USE IN THE POLYMERIZATION OF OLEFINS | BRASKEM AMERICA INC (US) | 2022-07-27 | — | — | EP | disclosed |
| CN-114478846-A | Carrier of catalyst with function of catalyzing olefin polymerization, preparation method and application of carrier, olefin polymerization catalyst and application of olefin polymerization catalyst | 中国石油化工股份有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-109694427-B | Polypropylene, preparation method and application thereof | 中国石油化工股份有限公司 | 2022-03-15 | — | — | CN | disclosed |
| CN-114085301-A | Solid catalyst component for preparing olefin polymer and application thereof | 中国石油化工股份有限公司 | 2022-02-25 | — | — | CN | disclosed |
| CN-109694429-B | Polypropylene, preparation method and application thereof | 中国石油化工股份有限公司 | 2022-01-04 | — | — | CN | disclosed |
| CN-113444189-A | Catalyst for olefin polymerization and application thereof | 中国石油化工股份有限公司 | 2021-09-28 | — | — | CN | disclosed |
| US-11117982-B2 | Non-phthalate catalyst system and its use in the polymerization of olefins | BRASKEM AMERICA, INC. (US) | 2021-09-14 | — | — | US | disclosed |
| CN-111234064-B | Solid catalyst component for olefin polymerization, olefin polymerization catalyst and application thereof | 中国石油化工股份有限公司 | 2021-08-03 | — | — | CN | disclosed |
| WO-2012017038-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2012-02-09 | — | — | WO | disclosed |
| EP-1472293-A4 | SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF | CHINA PETROLEUM & CHEMICAL (CN) | 2008-01-16 | — | — | EP | disclosed |
| CN-1982290-A | Fungicidal carboxamides | UNIV ARKANSAS (US) | 2007-06-20 | — | — | CN | disclosed |
| CN-1274724-C | Method of producing olefine polymer and its polymer | SINOPEC CORP (CN) | 2006-09-13 | — | — | CN | disclosed |
| CN-1241958-C | Propene polymers and preparation process thereof | CHINA PETROLEUM & CHEMICAL (CN) | 2006-02-15 | — | — | CN | disclosed |
| CN-1597714-A | Method of producing olefine polymer and its polymer | CHINA PETROCHEMICAL CORP (CN) | 2005-03-23 | — | — | CN | disclosed |
| CN-1566164-A | Propene polymers and preparation process thereof | SINOPEC CORP (CN) | 2005-01-19 | — | — | CN | disclosed |
| EP-1472293-A1 | SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF | China Petroleum & Chemical Corporation (CN) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003068828-A1 | SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2003-08-21 | — | — | WO | disclosed |
| EP-0416822-A2 | Stain-resistant plasticizer compositions and method of making same | VELSICOL CHEMICAL CORPORATION (US) | 1991-03-13 | — | — | EP | disclosed |