Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | DAO | P14920 | 1/20 | 0.56 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL560461 | 1.00 | TSHR (0.56) | TSHRDAONAPRTALDH1A1LMNA | |
| Benzoyl Formic Acid SCHEMBL28688590 | 0.91 | CES2 (0.50) | TSHRDAONAPRTALDH1A1LMNA | |
| Benzoic Acid SCHEMBL27592470 | 0.91 | DAO (0.47) | TSHRDAONAPRTALDH1A1LMNA | |
| Benzoic Acid SCHEMBL18036621 | 0.91 | DAO (0.47) | TSHRDAONAPRTALDH1A1LMNA | |
| Benzoic Acid SCHEMBL27522251 | 0.91 | DAO (0.47) | TSHRDAONAPRTALDH1A1LMNA | |
| Benzoic Acid SCHEMBL569952 | 0.91 | DAO (0.50) | TSHRDAONAPRTALDH1A1LMNA | |
| Benzoic Acid SCHEMBL27573797 | 0.89 | DAO (0.48) | TSHRDAONAPRTALDH1A1LMNA | |
| Benzoic Acid SCHEMBL28096523 | 0.88 | RARB (0.44) | TSHRDAONAPRTALDH1A1LMNA | |
| Benzoic Acid SCHEMBL27580914 | 0.88 | DAO (0.44) | TSHRDAONAPRTALDH1A1LMNA | |
| Benzoic Acid SCHEMBL28130949 | 0.88 | DAO (0.44) | TSHRDAONAPRTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116023552-A | Catalyst and catalyst system for olefin polymerization | 中国石油化工股份有限公司 | 2023-04-28 | — | — | CN | disclosed |