Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | DAO | P14920 | 1/20 | 0.56 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL28993296 | 1.00 | TSHR (0.56) | TSHRDAONAPRTALDH1A1LMNA | |
| Benzoyl Formic Acid SCHEMBL28688590 | 0.91 | CES2 (0.50) | TSHRDAONAPRTALDH1A1LMNA | |
| Benzoic Acid SCHEMBL27592470 | 0.91 | DAO (0.47) | TSHRDAONAPRTALDH1A1LMNA | |
| Benzoic Acid SCHEMBL18036621 | 0.91 | DAO (0.47) | TSHRDAONAPRTALDH1A1LMNA | |
| Benzoic Acid SCHEMBL27522251 | 0.91 | DAO (0.47) | TSHRDAONAPRTALDH1A1LMNA | |
| Benzoic Acid SCHEMBL569952 | 0.91 | DAO (0.50) | TSHRDAONAPRTALDH1A1LMNA | |
| Benzoic Acid SCHEMBL27573797 | 0.89 | DAO (0.48) | TSHRDAONAPRTALDH1A1LMNA | |
| Benzoic Acid SCHEMBL28096523 | 0.88 | RARB (0.44) | TSHRDAONAPRTALDH1A1LMNA | |
| Benzoic Acid SCHEMBL27580914 | 0.88 | DAO (0.44) | TSHRDAONAPRTALDH1A1LMNA | |
| Benzoic Acid SCHEMBL28130949 | 0.88 | DAO (0.44) | TSHRDAONAPRTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 596 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026103729-A1 | CATALYST SYSTEM, USE THEREOF, AND OLEFIN POLYMERIZATION METHOD | 中国石油化工股份有限公司 | 2026-05-21 | — | — | WO | claimed |
| CN-118290623-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118290625-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118290624-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-116041584-B | Catalyst component, preparation method thereof, catalyst system and application thereof | 中国石油化工股份有限公司 | 2024-05-07 | — | — | CN | claimed |
| CN-117964812-A | Alkoxy magnesium particles, and corresponding catalyst solid component and catalyst system thereof | 中国石油化工股份有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-117964813-A | Solid catalyst component and catalyst system for olefin polymerization and preparation method thereof | 中国石油化工股份有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-117946300-A | Olefin polymerization catalyst component, preparation method thereof, catalyst system and application | 中国石油化工股份有限公司 | 2024-04-30 | — | — | CN | claimed |
| CN-117924550-A | Magnesium-based solid and catalyst component for olefin polymerization, and preparation methods and applications thereof | 中国石油化工股份有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-117924549-A | Ziegler-Natta catalyst component, process for preparing the same, olefin polymerization catalyst and process for polymerizing olefin | 中国石油化工股份有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-102453147-B | Catalyst component, catalyst and method for olefin polymerization | CHINA PETROLEUM & CHEMICAL | 2013-06-05 | — | — | CN | claimed |
| CN-102453149-B | Olefin polymerization catalyst component, olefin polymerization catalyst and olefin polymerization method | CHINA PETROLEUM & CHEMICAL | 2013-06-05 | — | — | CN | claimed |
| CN-103012631-A | Preparation method of propylene polymer | CHINA PETROLEUM & CHEMICAL | 2013-04-03 | — | — | CN | claimed |
| CN-103012626-A | Olefin polymerization catalyst ingredient, preparation method of the olefin polymerization catalyst ingredient, catalyst system, use of the catalyst system, and olefin polymerization method | CHINA PETROLEUM & CHEMICAL | 2013-04-03 | — | — | CN | claimed |
| CN-103012625-A | Olefin polymerization catalyst ingredient, preparation method and use of the olefin polymerization catalyst ingredient, catalyst system, use of the catalyst system, and olefin polymerization method | CHINA PETROLEUM & CHEMICAL | 2013-04-03 | — | — | CN | claimed |
| CN-103012627-A | Olefin polymerization catalyst ingredient, preparation method and use of the olefin polymerization catalyst ingredient, catalyst system, use of the catalyst system, and olefin polymerization method | CHINA PETROLEUM & CHEMICAL | 2013-04-03 | — | — | CN | claimed |
| US-7388061-B2 | Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2008-06-17 | — | — | US | claimed |
| US-20050239636-A1 | Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2005-10-27 | — | — | US | claimed |
| US-20050096389-A1 | Polyol ester compounds useful in preparation of a catalyst for olefins polymerization, process for preparing the same and use thereof | CHINA PETROLEUM & CHEMICAL (CN) | 2005-05-05 | — | — | US | claimed |
| CN-1580034-A | Glycol ester compound for preparing catalyst for olefinic polymerization | CHINA PETROCHEMICAL CORP (CN) | 2005-02-16 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050096389-A1 | Polyol ester compounds useful in preparation of a catalyst for olefins polymerization, process for preparing the same and use thereof | CBR3, CBR1, OXER1 | TSHR 921/4885DAO 1971/4885NAPRT 1682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.