Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17417889 | 0.85 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPK1MAPTXBP1 | |
| SCHEMBL9654433 | 0.85 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPK1MAPTXBP1 | |
| SCHEMBL78385 | 0.85 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPK1MAPTXBP1 | |
| Etocrylene SCHEMBL7199053 | 0.81 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPK1MAPTRAB9A | |
| SCHEMBL9068628 | 0.80 | ALDH1A1 (0.52) | ALDH1A1LMNAMAPK1MAPTXBP1 | |
| SCHEMBL11408016 | 0.78 | ALDH1A1 (0.51) | ALDH1A1LMNAMAPK1MAPTXBP1 | |
| SCHEMBL18012244 | 0.78 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPK1NAAA | |
| SCHEMBL18012240 | 0.78 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPK1NAAA | |
| SCHEMBL18012239 | 0.78 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPK1NAAA | |
| SCHEMBL28676919 | 0.78 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPK1MAPTXBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060189731-A1 | Stabilizing composition for chlorine-containing polymers | ARKEMA FRANCE (FR) | 2006-08-24 | — | — | US | disclosed |
| US-20060148941-A1 | Monosubstituted 6-aminouracils for the stabilization of halogenated polymers | CHEMTURA VINYL ADDITIVES GMBH (DE) | 2006-07-06 | — | — | US | disclosed |
| EP-1669397-A1 | Stabilizing compositions for chlorine-containing polymers and resins | Arkema (FR) | 2006-06-14 | — | — | EP | disclosed |
| EP-1644435-A2 | STABILIZING COMPOSITION FOR CHLORINE-CONTAINING POLYMERS | ARKEMA (FR) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005005530-A2 | STABILIZING COMPOSITION FOR CHLORINE-CONTAINING POLYMERS | ARKEMA (FR) | 2005-01-20 | — | — | WO | disclosed |
| EP-1496083-A1 | Stabilizing composition for chlorine-containing polymers | ARKEMA (FR) | 2005-01-12 | — | — | EP | disclosed |
| US-6274654-B1 | 1,3-Disubstituted 6-aminouracils for stabilizing halogenated polymers | WITCO VINYL ADDITIVES GMBH (DE) | 2001-08-14 | — | — | US | disclosed |
| US-6211270-B1 | HEAT AND LIGHT STABILIZERS FOR POLYMERS | WITCO VINYL ADDITIVES GMBH (DE) | 2001-04-03 | — | — | US | disclosed |
| US-6174941-B1 | FOR STABILIZING CHLORINE CONTAINING POLYMERS SUCH AS POLYVINYL CHLORIDE | WITCO VINYL ADDITIVES GMBH (DE) | 2001-01-16 | — | — | US | disclosed |
| US-6156830-A | 5-substituted 6-aminouracils as stabilizers for halogenated polymers | WITCO VINYL ADDITIVES GMBH (DE) | 2000-12-05 | — | — | US | disclosed |
| US-6084013-A | MIXTURES OF SUBSTITUTED URACILS OR THIURACILS WITH ALUMINUM CALCIUM HYDROXIDES, PHOSPHITES AND CARBONATES OR THEIR HYDRATES, ALSO LITHIUM LAYERED LATTICE COMPOUNDS AND TITANIUM HYDROTALCITES, FOR POLYVINYL CHLORIDE | WITCO VINYL ADDITIVES GMBH (DE) | 2000-07-04 | — | — | US | disclosed |