Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.39 |
| ▸ | CTSG | P08311 | 2/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.39 |
| ▸ | CMA1 | P23946 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18012239 | 1.00 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPK1PRSS1CTSG | |
| SCHEMBL18012244 | 1.00 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPK1PRSS1CTSG | |
| SCHEMBL18012243 | 0.90 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPK1PRSS1CTSG | |
| SCHEMBL18012242 | 0.85 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPK1 | |
| SCHEMBL601710 | 0.84 | ALDH1A1 (0.63) | ALDH1A1LMNAMAPK1PRSS1CTSG | |
| SCHEMBL12832065 | 0.83 | ALDH1A1 (0.55) | ALDH1A1LMNAMAPK1PRSS1CTSG | |
| SCHEMBL4743756 | 0.81 | ALDH1A1 (0.67) | ALDH1A1LMNAMAPK1PRSS1CTSG | |
| SCHEMBL14877495 | 0.79 | ALDH1A1 (0.65) | ALDH1A1LMNAMAPK1CES2CES1 | |
| SCHEMBL7205837 | 0.79 | ALDH1A1 (0.65) | ALDH1A1LMNAMAPK1CES2CES1 | |
| SCHEMBL1123572 | 0.79 | ALDH1A1 (0.65) | ALDH1A1LMNAMAPK1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9726932-B2 | Optical film, optical compensation film, polarizing plate and liquid crystal display | FUJIFILM CORPORATION (JP) | 2017-08-08 | — | — | US | disclosed |
| US-20160231606-A1 | OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY | FUJIFILM CORPORATION (JP) | 2016-08-11 | — | — | US | disclosed |