Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 6/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.31 |
| ▸ | LYPLA1 | O75608 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5699571 | 1.00 | CCR2 (0.33) | CCR2CCR1CCR5CXCR4HDAC8 | |
| SCHEMBL1114567 | 1.00 | CCR2 (0.33) | CCR2CCR1CCR5CXCR4HDAC8 | |
| SCHEMBL1114805 | 1.00 | CCR2 (0.33) | CCR2CCR1CCR5CXCR4HDAC8 | |
| SCHEMBL1114885 | 0.87 | CCR2 (0.37) | CCR2CCR1CCR5CXCR4 | |
| SCHEMBL10476331 | 0.83 | CCR2 (0.44) | CCR2CCR1CCR5CXCR4LYPLA1 | |
| SCHEMBL1114595 | 0.80 | PSEN1 (0.38) | CCR2CCR1CCR5CXCR4HDAC8 | |
| SCHEMBL1114447 | 0.80 | PSEN1 (0.38) | CCR2CCR1CCR5CXCR4HDAC8 | |
| SCHEMBL1114579 | 0.80 | PSEN1 (0.38) | CCR2CCR1CCR5CXCR4HDAC8 | |
| SCHEMBL1114533 | 0.80 | PSEN1 (0.38) | CCR2CCR1CCR5CXCR4HDAC8 | |
| SCHEMBL1114763 | 0.80 | PSEN1 (0.38) | CCR2CCR1CCR5CXCR4HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1691814-A2 | ANTI-INFLAMMATORY AGENTS | CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LIMITED (GB) | 2006-08-23 | — | — | EP | claimed |