Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 10/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.42 |
| ▸ | LYPLA1 | O75608 | 1/20 | 0.30 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1114805 | 0.83 | CCR2 (0.33) | CCR2CCR1CCR5CXCR4LYPLA1 | |
| SCHEMBL5699574 | 0.83 | CCR2 (0.33) | CCR2CCR1CCR5CXCR4LYPLA1 | |
| SCHEMBL1114567 | 0.83 | CCR2 (0.33) | CCR2CCR1CCR5CXCR4LYPLA1 | |
| SCHEMBL5699571 | 0.83 | CCR2 (0.33) | CCR2CCR1CCR5CXCR4LYPLA1 | |
| SCHEMBL1114885 | 0.80 | CCR2 (0.37) | CCR2CCR1CCR5CXCR4NOD1 | |
| SCHEMBL5699577 | 0.78 | CCR2 (0.49) | CCR2CCR1CCR5CXCR4 | |
| SCHEMBL5699633 | 0.77 | CCR2 (0.40) | CCR2CCR1CCR5CXCR4NOD1 | |
| SCHEMBL1114657 | 0.73 | CCR2 (0.52) | CCR2CCR1CCR5CXCR4NOD1 | |
| SCHEMBL1114788 | 0.73 | CCR2 (0.52) | CCR2CCR1CCR5CXCR4NOD1 | |
| SCHEMBL5699632 | 0.73 | CCR2 (0.52) | CCR2CCR1CCR5CXCR4NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1691814-B9 | ANTI-INFLAMMATORY AGENTS | CAMBRIDGE ENTPR LTD (GB) | 2013-02-20 | — | — | EP | claimed |
| EP-1691814-B1 | ANTI-INFLAMMATORY AGENTS | CAMBRIDGE ENTPR LTD (GB) | 2012-07-25 | — | — | EP | claimed |