Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 17/20 | 0.50 |
| ▸ | RARB | P10826 | 11/20 | 0.48 |
| ▸ | RARA | P10276 | 10/20 | 0.48 |
| ▸ | RXRA | P19793 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL957818 | 0.84 | RARG (0.70) | RARGRARBRARARXRA | |
| SCHEMBL5699563 | 0.84 | RARG (0.54) | RARGRARBRARARXRAPPARG | |
| SCHEMBL957269 | 0.79 | RARG (0.57) | RARGRARBRARARXRA | |
| SCHEMBL7871229 | 0.78 | RARG (0.53) | RARGRARBRARARXRA | |
| SCHEMBL5846340 | 0.75 | RARB (0.77) | RARGRARBRARARXRA | |
| SCHEMBL958037 | 0.73 | RARG (0.72) | RARGRARBRARARXRA | |
| SCHEMBL5699564 | 0.73 | RARG (0.49) | RARGRARBRARARXRAPPARG | |
| SCHEMBL5699604 | 0.73 | RARG (0.47) | RARGRARBRARARXRAPPARG | |
| SCHEMBL2917289 | 0.73 | RARG (0.56) | RARGRARBRARARXRA | |
| SCHEMBL5699630 | 0.72 | RARG (0.48) | RARGRARBRARARXRAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692093-A1 | BIPHENYL DERIVATIVES USEFUL AS LIGANDS THAT ACTIVATE THE RAR RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development, S.N.C. (FR) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005056516-A1 | BIPHENYL DERIVATIVES USEFUL AS LIGANDS THAT ACTIVATE THE RAR RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2005-06-23 | — | — | WO | disclosed |