Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 17/20 | 0.53 |
| ▸ | RARB | P10826 | 12/20 | 0.53 |
| ▸ | RARA | P10276 | 10/20 | 0.53 |
| ▸ | RXRA | P19793 | 3/20 | 0.50 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5846043 | 0.83 | RARG (0.73) | RARGRARBRARARXRACYP26A1 | |
| SCHEMBL5846340 | 0.79 | RARB (0.77) | RARGRARBRARARXRA | |
| SCHEMBL5699563 | 0.78 | RARG (0.54) | RARGRARBRARARXRA | |
| SCHEMBL5699607 | 0.78 | RARG (0.50) | RARGRARBRARARXRA | |
| SCHEMBL5847739 | 0.76 | RARG (0.58) | RARGRARBRARARXRA | |
| SCHEMBL10549628 | 0.76 | RARG (0.57) | RARGRARBRARARXRA | |
| SCHEMBL498280 | 0.75 | RARB (0.76) | RARGRARBRARARXRA | |
| SCHEMBL9551739 | 0.74 | RARB (0.69) | RARGRARBRARARXRACYP26A1 | |
| SCHEMBL7265393 | 0.72 | RARG (0.63) | RARGRARBRARARXRA | |
| SCHEMBL2917289 | 0.72 | RARG (0.56) | RARGRARBRARARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316009-B1 | FOR THERAPY OF DERMATOLOGICAL COMPLAINTS ASSOCIATED WITH A KERATINIZATION DISORDER, AND FOR COMBATING AGEING OF THE SKIN | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2001-11-13 | — | — | US | disclosed |