SCHEMBL5700564

SCHEMBL5700564

C#Cc1cccnc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9959517 0.94 GRM5 (0.41)
SCHEMBL10847910 0.89 GRM5 (0.38)
SCHEMBL1859075 0.77
SCHEMBL119023 0.77
SCHEMBL29530718 0.77
SCHEMBL27711883 0.77 ALDH1A1 (0.47)
SCHEMBL29003 0.76 TDP1 (0.39)
SCHEMBL30800867 0.76 ALDH1A1 (0.46)
SCHEMBL981103 0.74 GRM5 (0.50)
SCHEMBL18188087 0.74 GRM5 (0.53)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240351959-A1 USE OF ETHYNYLPYRIDINE COMPOUNDS AS NITRIFICATION INHIBITORS BASF SE (DE) 2024-10-24 US disclosed
EP-4341245-A1 USE OF ETHYNYLPYRIDINE COMPOUNDS AS NITRIFICATION INHIBITORS BASF SE (DE) 2024-03-27 EP disclosed
CN-117355504-A Use of ethynyl pyridine compounds as nitrification inhibitors 巴斯夫欧洲公司 2024-01-05 CN disclosed
WO-2022243521-A1 USE OF ETHYNYLPYRIDINE COMPOUNDS AS NITRIFICATION INHIBITORS BASF SE (DE) 2022-11-24 WO disclosed
US-7601714-B2 Pyrimidine derivatives useful as inhibitors of PKC-theta BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 2009-10-13 US disclosed
EP-1270582-B1 TRIPHENYLPHOSPHINE DERIVATIVES, PALLADIUM OR NICKEL COMPLEXES THEREOF, AND PROCESS FOR PREPARING BIARYL DERIVATIVES MITSUBISHI RAYON CO (JP) 2006-08-30 EP disclosed
US-6693210-B2 USING PALLADIUM, NICKEL PHOSPHINE COMPLEX AS CATALYSTS MITSUBISHI RAYON CO., LTD. (JP) 2004-02-17 US disclosed
US-20030065208-A1 Using palladium, nickel phosphine complex as catalysts MITSUBISHI RAYON CO., LTD. (JP) 2003-04-03 US disclosed
EP-1270582-A1 TRIPHENYLPHOSPHINE DERIVATIVE, PRODUCTION PROCESS THEREFOR, PALLADIUM COMPLEX THEREOF, AND PROCESS FOR PRODUCING BIARYL DERIVATIVE Mitsubishi Rayon Co., Ltd. (JP) 2003-01-02 EP disclosed