SCHEMBL29003

SCHEMBL29003

C#Cc1cccnc1-c1ncccc1C#C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.39
TDP2 O95551 1/20 0.39
NSD2 O96028 1/20 0.39
ABL1 P00519 1/20 0.39
PLCG1 P19174 1/20 0.39
CES1 P23141 1/20 0.39
PAX8 Q06710 1/20 0.39
RIN1 Q13671 1/20 0.39
MEN1 O00255 1/20 0.39
THRB P10828 1/20 0.39
BLM P54132 1/20 0.39
KMT2A Q03164 1/20 0.39
GAA P10253 1/20 0.39
KDM4E B2RXH2 3/20 0.37
GRM5 P41594 1/20 0.37
CDC25B P30305 3/20 0.35
PTPRC P08575 2/20 0.35
S100A4 P26447 2/20 0.35
CTSL P07711 1/20 0.35
CTSS P25774 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8914679 0.85 PTGS1 (0.39) TDP1KMT2AKDM4ECDC25BPTPRC
SCHEMBL9715965 0.83 KDM4E (0.48) TDP1BLMKDM4EMAPTLMNA
SCHEMBL29428995 0.79 ALDH1A1 (0.40) TDP1TDP2NSD2ABL1PLCG1
SCHEMBL981103 0.78 GRM5 (0.50) TDP1PLCG1KDM4EGRM5HDAC8
SCHEMBL23581979 0.78 RORB (0.54)
SCHEMBL29865338 0.78 RORB (0.54)
SCHEMBL5700308 0.76
SCHEMBL510566 0.76
SCHEMBL4036995 0.76
SCHEMBL5700564 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180214827-A1 PERYLENE DIIMIDE BASED MEMBRANE AND METHODS OF USE THEREOF YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2018-08-02 US disclosed
EP-3319715-A1 PERYLENE DIIMIDE BASED MEMBRANE AND METHODS OF USE THEREOF Yeda Research and Development Co., Ltd. (IL) 2018-05-16 EP disclosed
EP-3067354-B1 SUPRAMOLECULAR POLYMERS DERIVED FROM PERYLENE-DIIMIDES YEDA RES & DEV (IL) 2018-01-03 EP disclosed
US-9701784-B2 Supramolecular polymers derived from perylene-diimides YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2017-07-11 US disclosed
US-9623381-B2 Separation of nanoparticles YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2017-04-18 US disclosed
WO-2017006325-A1 PERYLENE DIIMIDE BASED MEMBRANE AND METHODS OF USE THEREOF YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2017-01-12 WO disclosed
EP-3112013-A1 PERYLENE DIIMDE BASED MEMBRANE, PREPARATION AND RECYCLING THEREOF, AND USE FOR NANOPARTICLE SEPARATION THEREOF Yeda Research and Development Co. Ltd (IL) 2017-01-04 EP disclosed
EP-3067354-A1 SUPRAMOLECULAR POLYMERS DERIVED FROM PERYLENE-DIIMIDES Yeda Research and Development Co. Ltd. (IL) 2016-09-14 EP disclosed
US-20150375180-A1 SEPARATION OF NANOPARTICLES YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2015-12-31 US disclosed
US-20150240027-A1 SUPRAMOLECULAR POLYMERS DERIVED FROM PERYLENE-DIIMIDES YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2015-08-27 US disclosed
US-9067181-B2 Separation of nanoparticles YEDA RESEARCH AND DEVELOPMENT CO. LTD. (US) 2015-06-30 US disclosed
US-8968886-B2 Doubly reduced perylene-diimides and supramolecular polymers derived from perylene-diimides YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 2015-03-03 US disclosed
US-20130303769-A1 SEPARATION OF NANOPARTICLES YEDA RESEARCH AND DEVELOPMENT CO. LTD (IL) 2013-11-14 US disclosed
EP-2608874-A1 SEPARATION OF NANOPARTICLES Yeda Research and Development Co. Ltd. (IL) 2013-07-03 EP disclosed
WO-2012025928-A1 SEPARATION OF NANOPARTICLES YEDA RESEARCH AND DEVELOPMENT CO.LTD (IL) 2012-03-01 WO disclosed
US-20110101276-A1 DOUBLY REDUCED PERYLENE-DIIMIDES AND SUPRAMOLECULAR POLYMERS DERIVED FROM PERYLENE-DIIMIDES YEDA RESEARCH AND DEVELOPMENT CO.LTD (IL) 2011-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150240027-A1 SUPRAMOLECULAR POLYMERS DERIVED FROM PERYLENE-DIIMIDES PIN1, PARN, DDT TDP1 1031/4885TDP2 347/4885NSD2 1990/4885
US-20150375180-A1 SEPARATION OF NANOPARTICLES NCL, CD63, PARN TDP1 4190/4885TDP2 2663/4885NSD2 1121/4885
US-20110101276-A1 DOUBLY REDUCED PERYLENE-DIIMIDES AND SUPRAMOLECULAR POLYMERS DERIVED FROM PERYLENE-DIIMIDES NR2E3, NR2C2, NR0B2 TDP1 3663/4885TDP2 1002/4885NSD2 533/4885
US-20130303769-A1 SEPARATION OF NANOPARTICLES NCL, CD63, PARN TDP1 4190/4885TDP2 2663/4885NSD2 1121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.