Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 0.53 |
| ▸ | TACR1 | P25103 | 16/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | UGCG | Q16739 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5700750 | 1.00 | GHSR (0.53) | GHSRTACR1CYP3A4UGCG | |
| SCHEMBL12798415 | 0.84 | GHSR (0.53) | GHSRTACR1CYP3A4UGCG | |
| SCHEMBL5700753 | 0.84 | GHSR (0.55) | GHSRTACR1CYP3A4UGCG | |
| SCHEMBL7572185 | 0.83 | GHSR (0.52) | GHSRTACR1CYP3A4UGCG | |
| SCHEMBL12798440 | 0.80 | GHSR (0.49) | GHSRTACR1CYP3A4UGCG | |
| SCHEMBL7572189 | 0.79 | GHSR (0.47) | GHSRTACR1CYP3A4UGCG | |
| SCHEMBL8843163 | 0.75 | GHSR (0.47) | GHSRTACR1CYP3A4UGCG | |
| SCHEMBL5700751 | 0.74 | GHSR (0.40) | GHSRTACR1 | |
| SCHEMBL8311496 | 0.73 | GHSR (0.69) | GHSRTACR1CYP3A4UGCG | |
| SCHEMBL8311499 | 0.73 | GHSR (0.69) | GHSRTACR1CYP3A4UGCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870199-B1 | ASSAYS FOR GROWTH HORMONE SECRETAGOGUE RECEPTORS | MERCK & CO INC (US) | 2006-07-26 | — | — | EP | disclosed |
| EP-0876402-B1 | GROWTH HORMONE SECRETAGOGUE RECEPTOR FAMILY | MERCK & CO INC (US) | 2004-10-13 | — | — | EP | disclosed |
| US-20030166144-A1 | Growth hormone secretagogue receptor family | MERCK & CO., INC. (US) | 2003-09-04 | — | — | US | disclosed |
| US-6531314-B1 | Isolated from swine and of given amino acid sequence; can be used in drug screening for treating deficient children, patients with musculoskeletal impairment and recovering from hip fracture/osteoporosis. | MERCK & CO., INC. | 2003-03-11 | — | — | US | disclosed |
| US-6242199-B1 | DETECTING LIGAND ASSOCIATED WITH HORMONE RELEASE; TRANSFORM CELLS WITH VECTOR, TRANSFORM CELLS WITH VECTOR CODING LIGHT PROTEIN, INCUBATE CELLS WITH BINDING PROTEIN, DETECT BINDING ACTIVITY | MERCK & CO., INC. | 2001-06-05 | — | — | US | disclosed |