SCHEMBL5700760

SCHEMBL5700760

C=CCO[Si](OCC=C)(OCC=C)C(=O)C=C

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.32
TSHR P16473 1/20 0.31
MAPT P10636 1/20 0.31
CACNA1B Q00975 1/20 0.31
APBA1 Q02410 1/20 0.31
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
MAPK1 P28482 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propane SCHEMBL27604335 0.84 TSHR (0.33) TSHRALDH1A1
SCHEMBL2843011 0.76 ALDH1A1 (0.39) CYP3A4TSHRALDH1A1TP53MAPK1
SCHEMBL29047230 0.73 CYP3A4 (0.31) CYP3A4
SCHEMBL15212537 0.73 TSHR (0.41) CYP3A4TSHRALDH1A1TP53HIF1A
SCHEMBL29047231 0.68 ALDH1A1 (0.36) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL1724859 0.67 ALDH1A1 (0.38) TSHRALDH1A1
SCHEMBL28028849 0.67 TSHR (0.34) TSHRALDH1A1
Bicarbonate SCHEMBL10012606 0.67 TSHR (0.34) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL180320 0.66 TSHR (0.32) TSHR
SCHEMBL4544256 0.66 TSHR (0.32) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7094306-B2 Photocurable organic polymer composition DOW CORNING TORAY SILICONE CO., LTD. (JP) 2006-08-22 US disclosed
EP-1456251-B1 PHOTOCURABLE ORGANIC POLYMER COMPOSITION DOW CORNING TORAY SILICONE (JP) 2006-08-09 EP disclosed
US-20050090574-A1 Photocurable organic polymer composition DOW CORNING TORAY SILICONE CO. LTD (JP) 2005-04-28 US disclosed
EP-1456251-A1 PHOTOCURABLE ORGANIC POLYMER COMPOSITION Dow Corning Toray Silicone Company, Ltd. (JP) 2004-09-15 EP disclosed
WO-2003051933-A1 PHOTOCURABLE ORGANIC POLYMER COMPOSITION DOW CORNING TORAY SILICONE CO., LTD. (JP) 2003-06-26 WO disclosed