Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL504847 | 0.79 | PLCG1 (0.51) | SMN1; SMN2L3MBTL1ALDH1A1KCNN4KDM4E | |
| SCHEMBL28403522 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1ALDH1A1KCNN4KDM4E | |
| SCHEMBL11001068 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1ALDH1A1KCNN4KDM4E | |
| SCHEMBL20166133 | 0.78 | AHR (0.47) | SMN1; SMN2L3MBTL1ALDH1A1KCNN4KDM4E | |
| SCHEMBL10334728 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2L3MBTL1ALDH1A1KCNN4KDM4E | |
| SCHEMBL9978324 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2L3MBTL1ALDH1A1KCNN4KDM4E | |
| SCHEMBL75592 | 0.77 | KDM4E (0.41) | SMN1; SMN2L3MBTL1ALDH1A1CASP1KCNN4 | |
| SCHEMBL1027526 | 0.77 | AHR (0.46) | SMN1; SMN2L3MBTL1KCNN4KDM4EAHR | |
| SCHEMBL6120105 | 0.76 | LMNA (0.42) | SMN1; SMN2L3MBTL1ALDH1A1CASP1KDM4E | |
| SCHEMBL11721606 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2L3MBTL1ALDH1A1CASP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027328-B1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LTD (GB) | 2006-08-23 | — | — | EP | disclosed |
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |
| EP-1027328-A1 | SUBSTITUTED ANILIDES | Aventis Pharma Limited (GB) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999023063-A1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LIMITED (GB) | 1999-05-14 | — | — | WO | disclosed |