Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | AHR | P35869 | 2/20 | 0.43 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL504847 | 0.84 | PLCG1 (0.51) | SMN1; SMN2L3MBTL1AHRPLCG1SRC | |
| SCHEMBL20166133 | 0.83 | AHR (0.47) | SMN1; SMN2L3MBTL1AHRPLCG1SRC | |
| SCHEMBL9978324 | 0.83 | SMN1; SMN2 (0.46) | SMN1; SMN2L3MBTL1AHRPLCG1SRC | |
| SCHEMBL1027526 | 0.81 | AHR (0.46) | SMN1; SMN2L3MBTL1AHRPLCG1KCNN4 | |
| SCHEMBL28403522 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1AHRPLCG1SRC | |
| SCHEMBL1827357 | 0.80 | L3MBTL1 (0.55) | SMN1; SMN2L3MBTL1AHRBLMCYP2D6 | |
| SCHEMBL10334728 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2L3MBTL1AHRPLCG1SRC | |
| Hydrochloric Acid SCHEMBL17102116 | 0.79 | L3MBTL1 (0.53) | SMN1; SMN2L3MBTL1AHRBLMCYP2D6 | |
| SCHEMBL5700780 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2L3MBTL1AHRPLCG1SRC | |
| SCHEMBL28535906 | 0.77 | ALDH1A1 (0.43) | SMN1; SMN2L3MBTL1AHRPLCG1KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4535092-A | Acylanilides having antiandrogenic activity | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-08-13 | — | — | US | disclosed |
| EP-0079191-A1 | Amide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-05-18 | — | — | EP | disclosed |