Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.44 |
| ▸ | KIF11 | P52732 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | KDM5C | P41229 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.42 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dipyridyl SCHEMBL28142702 | 0.87 | KDM4E (0.45) | SLC1A5KIF11KDM4EKDM6BKDM4A | |
| Dipyridyl SCHEMBL28142700 | 0.85 | KDM4E (0.44) | SLC1A5KIF11KDM4EKDM6BKDM4A | |
| Dipyridyl SCHEMBL5700781 | 0.84 | KDM4E (0.46) | SLC1A5KIF11KDM4EKDM6BKDM4A | |
| SCHEMBL25413647 | 0.81 | ALDH1A1 (0.47) | SLC1A5KIF11POLBALDH1A1MAPT | |
| SCHEMBL25413645 | 0.81 | ALDH1A1 (0.47) | SLC1A5KIF11POLBALDH1A1MAPT | |
| Dipyridyl SCHEMBL28467381 | 0.78 | GSR (0.57) | SLC1A5KIF11KDM4EKDM6BKDM4A | |
| Dipyridyl SCHEMBL28201983 | 0.78 | GSR (0.57) | SLC1A5KIF11KDM4EKDM6BKDM4A | |
| Dl-Phenylalanine SCHEMBL27778634 | 0.77 | SLC7A5 (0.71) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Dipyridyl SCHEMBL28982601 | 0.76 | SLC1A5 (0.45) | SLC1A5KIF11KDM4EKDM6BKDM4A | |
| Dipyridyl SCHEMBL28074166 | 0.76 | GRM4 (0.47) | SLC1A5POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1512006-B1 | ELECTROSPRAY TANDEM MASS SPECTROMETRY FOR NEWBORN SCREENING | IZAAK WALTON KILLAM HEALTH CT (CA) | 2006-08-09 | — | — | EP | disclosed |
| EP-1512006-A1 | ELECTROSPRAY TANDEM MASS SPECTROMETRY FOR NEWBORN SCREENING | Izaak Walton Killam Health Centre (CA) | 2005-03-09 | — | — | EP | disclosed |
| US-6800489-B2 | Electrospray tandem mass spectrometry of transition metal diimine complexes of amino acids, α-hydroxyketones and hexose phosphates for newborn screening | IZAAK WALTON KILLAM HEALTH CENTER (CA) | 2004-10-05 | — | — | US | disclosed |
| WO-2003104802-A1 | ELECTROSPRAY TANDEM MASS SPECTROMETRY FOR NEWBORN SCREENING | IZAAK WALTON KILLAM HEALTH CENTRE (CA) | 2003-12-18 | — | — | WO | disclosed |
| US-20030228704-A1 | Electrospray tandem mass spectrometry of transition metal diimine complexes of amino acids, alpha-hydroxyketones and hexose phosphates for newborn screening | IZAAK WALTON KILLAM HEALTH CENTRE (CA) | 2003-12-11 | — | — | US | disclosed |