Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | EEF2K | O00418 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5700825 | 1.00 | ALDH1A1 (0.52) | ALDH1A1ATML3MBTL1EEF2KKMT2A | |
| SCHEMBL5700901 | 0.86 | SLC1A3 (0.47) | ALDH1A1ATML3MBTL1EEF2KSLC1A3 | |
| SCHEMBL5700908 | 0.86 | SLC1A3 (0.47) | ALDH1A1ATML3MBTL1EEF2KSLC1A3 | |
| SCHEMBL7189013 | 0.80 | ALDH1A1 (0.50) | ALDH1A1ATML3MBTL1EEF2KKMT2A | |
| SCHEMBL13780961 | 0.78 | CYP1A2 (0.55) | ALDH1A1ATML3MBTL1EEF2KKMT2A | |
| SCHEMBL2933326 | 0.78 | CYP1A2 (0.55) | ALDH1A1ATML3MBTL1EEF2KKMT2A | |
| SCHEMBL1735426 | 0.76 | SMN1; SMN2 (0.46) | ALDH1A1ATML3MBTL1MMP2MMP9 | |
| SCHEMBL3837360 | 0.76 | ALDH1A1 (0.54) | ALDH1A1ATML3MBTL1EEF2KKMT2A | |
| SCHEMBL7145763 | 0.76 | ALDH1A1 (0.54) | ALDH1A1ATML3MBTL1EEF2KKMT2A | |
| SCHEMBL5700925 | 0.76 | MEN1 (0.60) | KMT2ACYP3A4CYP2C9CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027328-B1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LTD (GB) | 2006-08-23 | — | — | EP | disclosed |
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |