Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.40 |
| ▸ | ITGAV | P06756 | 2/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | EEF2K | O00418 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5700908 | 1.00 | SLC1A3 (0.47) | SLC1A3SLC1A2SLC1A1KCNA5SMN1; SMN2 | |
| SCHEMBL5700833 | 0.86 | ALDH1A1 (0.52) | SLC1A3SLC1A2SLC1A1KEAP1ITGAV | |
| SCHEMBL5700825 | 0.86 | ALDH1A1 (0.52) | SLC1A3SLC1A2SLC1A1KEAP1ITGAV | |
| SCHEMBL13418143 | 0.84 | KCNA5 (0.45) | SLC1A3SLC1A2SLC1A1KCNA5ITGAV | |
| SCHEMBL5700886 | 0.77 | MEN1 (0.48) | KCNA5SMN1; SMN2ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL5700880 | 0.77 | MEN1 (0.48) | KCNA5SMN1; SMN2ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL27545824 | 0.72 | SLC1A3 (0.51) | SLC1A3SLC1A2SLC1A1ITGAVITGB3 | |
| SCHEMBL7400984 | 0.72 | SLC1A3 (0.53) | SLC1A3SLC1A2SLC1A1SMN1; SMN2KEAP1 | |
| SCHEMBL7400979 | 0.72 | SLC1A3 (0.53) | SLC1A3SLC1A2SLC1A1SMN1; SMN2KEAP1 | |
| SCHEMBL13418141 | 0.71 | EEF2K (0.50) | SLC1A3SLC1A2SLC1A1ITGAVITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027328-B1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LTD (GB) | 2006-08-23 | — | — | EP | disclosed |
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |