Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 19/20 | 0.66 |
| ▸ | ITGA4 | P13612 | 19/20 | 0.66 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5700922 | 1.00 | ITGB1 (0.66) | ITGB1ITGA4ITGB7KDM4EALDH1A1 | |
| SCHEMBL5700769 | 0.94 | ITGA4 (0.60) | ITGB1ITGA4KDM4EALDH1A1MAPT | |
| SCHEMBL5700777 | 0.94 | ITGA4 (0.60) | ITGB1ITGA4KDM4EALDH1A1MAPT | |
| SCHEMBL5705104 | 0.87 | ITGB1 (0.76) | ITGB1ITGA4ITGB7ALDH1A1KMT2A | |
| SCHEMBL5705101 | 0.87 | ITGB1 (0.76) | ITGB1ITGA4ITGB7ALDH1A1KMT2A | |
| SCHEMBL5701000 | 0.85 | ITGB1 (0.76) | ITGB1ITGA4ITGB7KMT2A | |
| SCHEMBL5700997 | 0.85 | ITGB1 (0.76) | ITGB1ITGA4ITGB7KMT2A | |
| SCHEMBL7531775 | 0.84 | ITGB1 (0.44) | ITGB1ITGA4ITGB7KMT2A | |
| SCHEMBL5700977 | 0.83 | ITGB1 (0.68) | ITGB1ITGA4ITGB7KMT2A | |
| SCHEMBL5700988 | 0.83 | ITGB1 (0.68) | ITGB1ITGA4ITGB7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027328-B1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LTD (GB) | 2006-08-23 | — | — | EP | disclosed |
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |