Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 9/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 9/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.37 |
| ▸ | ITGAV | P06756 | 5/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5700916 | 0.84 | ITGB1 (0.66) | ITGB1ITGA4ITGB7KMT2A | |
| SCHEMBL5700922 | 0.84 | ITGB1 (0.66) | ITGB1ITGA4ITGB7KMT2A | |
| SCHEMBL7477585 | 0.83 | ITGB3 (0.47) | ITGB1ITGA4ITGB3ITGAVKMT2A | |
| SCHEMBL5700984 | 0.81 | ITGB1 (0.51) | ITGB1ITGA4ITGB7KMT2AMEN1 | |
| SCHEMBL5700989 | 0.81 | ITGB1 (0.51) | ITGB1ITGA4ITGB7KMT2AMEN1 | |
| SCHEMBL5700996 | 0.81 | ITGB1 (0.51) | ITGB1ITGA4ITGB7KMT2AMEN1 | |
| SCHEMBL5700993 | 0.81 | ITGB1 (0.51) | ITGB1ITGA4ITGB7KMT2AMEN1 | |
| Water SCHEMBL7651150 | 0.81 | ITGB1 (0.51) | ITGB1ITGA4ITGB7KMT2AMEN1 | |
| Water SCHEMBL7651153 | 0.81 | ITGB1 (0.51) | ITGB1ITGA4ITGB7KMT2AMEN1 | |
| SCHEMBL7651701 | 0.79 | ITGB1 (0.49) | ITGB1ITGA4LMNAITGB7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |
| EP-1027328-A1 | SUBSTITUTED ANILIDES | Aventis Pharma Limited (GB) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999023063-A1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LIMITED (GB) | 1999-05-14 | — | — | WO | disclosed |