Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TACR3 | P29371 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5700926 | 1.00 | POLB (0.43) | POLBMEN1KMT2ATACR3TSHR | |
| SCHEMBL7388965 | 0.86 | POLB (0.42) | POLBMEN1KMT2ATACR3TSHR | |
| SCHEMBL5701087 | 0.86 | POLB (0.42) | POLBMEN1KMT2ATACR3TSHR | |
| SCHEMBL5700864 | 0.78 | KMT2A (0.44) | POLBMEN1KMT2ATACR3SMN1; SMN2 | |
| SCHEMBL5700869 | 0.78 | KMT2A (0.44) | POLBMEN1KMT2ATACR3SMN1; SMN2 | |
| SCHEMBL4029008 | 0.78 | TSHR (0.41) | POLBMEN1KMT2ATACR3TSHR | |
| SCHEMBL4029006 | 0.78 | TSHR (0.41) | POLBMEN1KMT2ATACR3TSHR | |
| SCHEMBL5700998 | 0.76 | TSHR (0.41) | POLBMEN1KMT2ATACR3TSHR | |
| SCHEMBL5700994 | 0.76 | TSHR (0.41) | POLBMEN1KMT2ATACR3TSHR | |
| SCHEMBL5700932 | 0.75 | MEN1 (0.60) | POLBMEN1KMT2ATACR3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027328-B1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LTD (GB) | 2006-08-23 | — | — | EP | disclosed |
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |