Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ITGB1 | P05556 | 10/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.50 |
| ▸ | ITGAV | P06756 | 2/20 | 0.50 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | DDX3X | O00571 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 9/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5155328 | 0.87 | ITGB1 (0.57) | MEN1KMT2AITGB1ITGB3ITGAV | |
| SCHEMBL5156432 | 0.82 | ITGB1 (0.52) | MEN1KMT2AITGB1ITGB3ITGAV | |
| SCHEMBL5156956 | 0.82 | ITGB1 (0.52) | MEN1KMT2AITGB1ITGB3ITGAV | |
| SCHEMBL4683165 | 0.80 | ITGA4 (0.67) | MEN1KMT2AITGB1ITGB3ITGAV | |
| SCHEMBL5700810 | 0.80 | ITGB1 (0.50) | MEN1KMT2AITGB1ITGB3ITGAV | |
| SCHEMBL29612679 | 0.79 | ITGB1 (0.67) | MEN1KMT2AITGB1ITGB3ITGAV | |
| SCHEMBL3485567 | 0.79 | ITGB1 (0.67) | MEN1KMT2AITGB1ITGB3ITGAV | |
| SCHEMBL5701113 | 0.78 | ITGB1 (0.59) | ITGB1ITGA4 | |
| SCHEMBL5701121 | 0.78 | ITGB1 (0.59) | ITGB1ITGA4 | |
| SCHEMBL5700969 | 0.78 | ITGB1 (0.48) | MEN1KMT2AITGB1ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027328-B1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LTD (GB) | 2006-08-23 | — | — | EP | disclosed |
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |
| EP-1027328-A1 | SUBSTITUTED ANILIDES | Aventis Pharma Limited (GB) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999023063-A1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LIMITED (GB) | 1999-05-14 | — | — | WO | disclosed |