Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 10/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.48 |
| ▸ | ITGAV | P06756 | 2/20 | 0.48 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 9/20 | 0.46 |
| ▸ | DDX3X | O00571 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5155328 | 0.85 | ITGB1 (0.57) | ITGB1ITGB3ITGAVITGA5ITGA4 | |
| SCHEMBL5156432 | 0.80 | ITGB1 (0.52) | ITGB1ITGB3ITGAVITGA5ITGA4 | |
| SCHEMBL5156956 | 0.80 | ITGB1 (0.52) | ITGB1ITGB3ITGAVITGA5ITGA4 | |
| SCHEMBL5700972 | 0.79 | ITGB1 (0.57) | ITGB1ITGA4 | |
| SCHEMBL5700975 | 0.79 | ITGB1 (0.57) | ITGB1ITGA4 | |
| SCHEMBL4683165 | 0.78 | ITGA4 (0.67) | ITGB1ITGB3ITGAVITGA5ITGA4 | |
| SCHEMBL5700810 | 0.78 | ITGB1 (0.50) | ITGB1ITGB3ITGAVITGA5ITGA4 | |
| SCHEMBL5700960 | 0.78 | MEN1 (0.51) | ITGB1ITGB3ITGAVITGA5ITGA4 | |
| SCHEMBL29612679 | 0.77 | ITGB1 (0.67) | ITGB1ITGB3ITGAVITGA5ITGA4 | |
| SCHEMBL3485567 | 0.77 | ITGB1 (0.67) | ITGB1ITGB3ITGAVITGA5ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027328-B1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LTD (GB) | 2006-08-23 | — | — | EP | disclosed |
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |
| EP-1027328-A1 | SUBSTITUTED ANILIDES | Aventis Pharma Limited (GB) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999023063-A1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LIMITED (GB) | 1999-05-14 | — | — | WO | disclosed |