Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5701021 | 1.00 | MAPT (0.50) | MAPTMEN1KMT2ALMNAGFER | |
| SCHEMBL5700932 | 0.81 | MEN1 (0.60) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL5700925 | 0.81 | MEN1 (0.60) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL5700869 | 0.78 | KMT2A (0.44) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL5700864 | 0.78 | KMT2A (0.44) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL5701002 | 0.77 | MAPT (0.49) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL5700999 | 0.77 | MAPT (0.49) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL4029008 | 0.75 | TSHR (0.41) | MAPTMEN1KMT2ARAB9AHTT | |
| SCHEMBL4029006 | 0.75 | TSHR (0.41) | MAPTMEN1KMT2ARAB9AHTT | |
| SCHEMBL5700880 | 0.75 | MEN1 (0.48) | MEN1KMT2ALMNASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027328-B1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LTD (GB) | 2006-08-23 | — | — | EP | disclosed |
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |