Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ASPH | Q12797 | 1/20 | 0.35 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21620889 | 0.75 | LRRK2 (0.34) | LIMK1 | |
| SCHEMBL570533 | 0.75 | HAO1 (0.50) | HCAR2HAO1KDM4E | |
| SCHEMBL15890593 | 0.74 | LRRK2 (0.36) | LIMK1 | |
| SCHEMBL12473490 | 0.74 | PPARG (0.44) | KDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL9444673 | 0.73 | HAO1 (0.49) | HCAR2HAO1KDM4E | |
| SCHEMBL16680727 | 0.72 | NOS2 (0.45) | LIMK1KMT2A | |
| SCHEMBL17837494 | 0.72 | LRRK2 (0.34) | LIMK1 | |
| SCHEMBL16517408 | 0.71 | MAPT (0.32) | HAO1KDM4EASPHKDM8 | |
| SCHEMBL16517436 | 0.71 | LRRK2 (0.48) | HCAR2HAO1KDM4EASPHKDM8 | |
| SCHEMBL18074314 | 0.70 | LIMK1 (0.34) | LIMK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601208-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | Graffinity Pharmaceuticals GmbH (DE) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012017021-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-09 | — | — | WO | disclosed |