SCHEMBL5701485

SCHEMBL5701485

C1=Cc2ccccc21.CCO[SiH](OCC)OCC

nearest known ligand 0.32

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RET P07949 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
P2RX4 Q99571 3/20 0.32
P2RX1 P51575 2/20 0.32
P2RX3 P56373 2/20 0.32
PTBP1 P26599 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
P2RX7 Q99572 1/20 0.32
ALDH1A1 P00352 1/20 0.31
HTR2A P28223 1/20 0.31
TSHR P16473 1/20 0.31
LTA4H P09960 1/20 0.31
SETD7 Q8WTS6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL27657019 0.81 TSHR (0.52) GAATSHRLTA4H
Naphthalene SCHEMBL28826709 0.80 CYP2A6 (0.42) GAAALDH1A1TSHRLTA4H
Biphenyl SCHEMBL3480054 0.78 ALDH1A1 (0.45) MAPTSMN1; SMN2ALDH1A1LTA4H
Ether SCHEMBL9798107 0.77 MAPT (0.36) RETGAAMAPTP2RX4P2RX1
Anthracene SCHEMBL4585948 0.76 CYP2A6 (0.41) GAAMAPTSMN1; SMN2ALDH1A1LTA4H
Benzene SCHEMBL27590784 0.76
Aniline SCHEMBL2797779 0.74 TSHR (0.50) GAAMAPTSMN1; SMN2ALDH1A1TSHR
SCHEMBL4585435 0.74 CYP2A6 (0.40) GAAMAPTSMN1; SMN2ALDH1A1LTA4H
Phenol SCHEMBL2348046 0.74 CA12 (0.50) GAAMAPTALDH1A1TSHRLTA4H
Benz(B)Anthracene SCHEMBL4585299 0.74 CYP2A6 (0.40) GAAMAPTSMN1; SMN2ALDH1A1LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117148676-A Negative photoresist composition for organic insulating film of liquid crystal display element 烟台希尔德材料科技有限公司 2023-12-01 CN disclosed
US-20160299376-A1 LIQUID CRYSTAL DISPLAY DEVICE, RADIATION-SENSITIVE RESIN COMPOSITION, INTERLAYER INSULATING FILM, METHOD FOR PRODUCING INTERLAYER INSULATING FILM, AND METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE JSR CORPORATION (JP) 2016-10-13 US disclosed
US-20140014928-A1 ORGANIC EL ELEMENT, RADIATION-SENSITIVE RESIN COMPOSITION, AND CURED FILM JSR CORPORATION (JP) 2014-01-16 US disclosed
EP-1510520-B1 Preparation of branched siloxane SHINETSU CHEMICAL CO (JP) 2006-07-26 EP disclosed
US-6943264-B2 Preparation of branched siloxane SHIN-ETSU CHEMICAL, CO., LTD. (JP) 2005-09-13 US disclosed
US-20050049427-A1 Preparation of branched siloxane SHIN-ETSU CHEMICAL CO., LTD. (JP) 2005-03-03 US disclosed
EP-1510520-A1 Preparation of branched siloxane Shin-Etsu Chemical Co., Ltd. (JP) 2005-03-02 EP disclosed