Aniline

Aniline

SCHEMBL2797779

CCO[SiH](OCC)OCC.Nc1ccccc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
TDP1 Q9NUW8 3/20 0.41
CYP3A4 P08684 4/20 0.41
TP53 P04637 1/20 0.41
ALDH1A1 P00352 2/20 0.39
MAOB P27338 7/20 0.38
MAOA P21397 6/20 0.38
MAPT P10636 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
CYP1A2 P05177 2/20 0.38
KDM4E B2RXH2 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
TAAR1 Q96RJ0 1/20 0.37
HSD17B10 Q99714 1/20 0.37
RAB9A P51151 2/20 0.36
GAA P10253 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aniline SCHEMBL14802038 0.98 TSHR (0.48) TSHRTDP1CYP3A4TP53ALDH1A1
Aniline SCHEMBL27575192 0.98 TSHR (0.48) TSHRTDP1CYP3A4TP53ALDH1A1
Aniline SCHEMBL224547 0.94 TSHR (0.44) TSHRTDP1CYP3A4TP53ALDH1A1
Biphenyl SCHEMBL3480054 0.81 ALDH1A1 (0.45) TP53ALDH1A1MAPTL3MBTL1KDM4E
Benzene SCHEMBL27590784 0.80
Aniline SCHEMBL15063338 0.79 TSHR (0.42) TSHRTDP1CYP3A4TP53ALDH1A1
Aniline SCHEMBL28307356 0.79 TSHR (0.42) TSHRTDP1CYP3A4TP53ALDH1A1
Toluene SCHEMBL27657019 0.79 TSHR (0.52) TSHRTP53CYP2C19RAB9AGAA
Naphthalene SCHEMBL28826709 0.78 CYP2A6 (0.42) TSHRTDP1TP53ALDH1A1L3MBTL1
Aniline SCHEMBL914934 0.78 TSHR (0.58) TSHRTDP1CYP3A4TP53ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105646895-A Attapulgite coated polyaniline anticorrosive material, preparation method and applications thereof 中国科学院宁波材料技术与工程研究所 2016-06-08 CN claimed
CN-105646895-A Attapulgite coated polyaniline anticorrosive material, preparation method and applications thereof 中国科学院宁波材料技术与工程研究所 2016-06-08 CN disclosed
CN-103483523-A Polyurethane foam added with modified attapulgite ANHUI JIFENG ENERGY SAVING MATERIAL CO LTD 2014-01-01 CN disclosed
US-8197591-B2 Pearlescent pigments having a secondary coating comprising α-silanes and method for the production thereof ECKART GMBH (DE) 2012-06-12 US disclosed
CN-101203546-B Crosslinkable fluorine-containing aromatic prepolymer and use thereof ASAHI GLASS CO.,LTD. (JP) 2012-02-01 CN disclosed
US-20100163420-A1 METAL EFFECT PIGMENTS FOR USE IN THE CATHODIC ELECTRODEPOSITION PAINTING, METHOD FOR THE PRODUCTION AND USE OF THE SAME, AND ELECTRODEPOSITION PAINT ECKART GMBH (DE) 2010-07-01 US disclosed
US-20090249979-A1 PEARLESCENT PIGMENTS HAVING A SECONDARY COATING COMPRISING ALPHA-SILANES AND METHOD FOR THE PRODUCTION THEREOF ECKART GMBH (DE) 2009-10-08 US disclosed
CN-101203546-A Crosslinkable fluorine-containing aromatic prepolymer and use thereof ASAHI GLASS CO LTD (JP) 2008-06-18 CN disclosed
EP-1100093-A2 Flame-resistant resin composition and electric wire having a layer thereof Mitsubishi Cable Industries, Ltd. (JP) 2001-05-16 EP disclosed