SCHEMBL5701575

SCHEMBL5701575

CCO[Si](O[SiH](C)C)(O[SiH](C)C)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.34
RELA Q04206 1/20 0.32
KDM4E B2RXH2 1/20 0.31
NPC1 O15118 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
HPGD P15428 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12136741 0.84 KDM4E (0.30) LTA4HKDM4ENPC1ALDH1A1TP53
SCHEMBL29900 0.83 LTA4H (0.37) LTA4HRELAKDM4ENPC1ALDH1A1
SCHEMBL94175 0.83 ESR1 (0.33)
Ammonia Solution, Strong SCHEMBL28965973 0.81 LTA4H (0.35) LTA4HRELAKDM4ENPC1ALDH1A1
SCHEMBL20493844 0.81 ESR1 (0.32)
Ethane SCHEMBL28129535 0.81 LTA4H (0.35) LTA4HRELAKDM4ENPC1ALDH1A1
SCHEMBL8415484 0.81 LTA4H (0.35) LTA4HRELAKDM4ENPC1ALDH1A1
SCHEMBL10495731 0.81 LTA4H (0.35) LTA4HRELAKDM4ENPC1ALDH1A1
Water SCHEMBL27611436 0.81 LTA4H (0.35) LTA4HRELAKDM4ENPC1ALDH1A1
Methane SCHEMBL27804293 0.81 LTA4H (0.35) LTA4HRELAKDM4ENPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7241851-B2 Silicone condensation reaction MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2007-07-10 US disclosed
EP-1510520-B1 Preparation of branched siloxane SHINETSU CHEMICAL CO (JP) 2006-07-26 EP disclosed
US-6943264-B2 Preparation of branched siloxane SHIN-ETSU CHEMICAL, CO., LTD. (JP) 2005-09-13 US disclosed
US-20050049427-A1 Preparation of branched siloxane SHIN-ETSU CHEMICAL CO., LTD. (JP) 2005-03-03 US disclosed
EP-1510520-A1 Preparation of branched siloxane Shin-Etsu Chemical Co., Ltd. (JP) 2005-03-02 EP disclosed