SCHEMBL5701624

SCHEMBL5701624

CO[Si](CCCCl)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1257228 0.88 TSHR (0.30)
SCHEMBL12995304 0.83 LMNA (0.38) LMNA
SCHEMBL37352 0.83 LMNA (0.40) LMNA
SCHEMBL2295080 0.80 LMNA (0.39) LMNA
Hydrochloric Acid SCHEMBL30565104 0.80 LMNA (0.39) LMNA
Ammonia Solution, Strong SCHEMBL2783441 0.80 LMNA (0.39) LMNA
Ethane SCHEMBL28073218 0.80 LMNA (0.39) LMNA
SCHEMBL5701756 0.78
SCHEMBL5701623 0.78 LMNA (0.32) LMNA
Hydrogen Sulfide SCHEMBL7795173 0.78 LMNA (0.42) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1510520-B1 Preparation of branched siloxane SHINETSU CHEMICAL CO (JP) 2006-07-26 EP disclosed
US-6943264-B2 Preparation of branched siloxane SHIN-ETSU CHEMICAL, CO., LTD. (JP) 2005-09-13 US disclosed
US-20050049427-A1 Preparation of branched siloxane SHIN-ETSU CHEMICAL CO., LTD. (JP) 2005-03-03 US disclosed
EP-1510520-A1 Preparation of branched siloxane Shin-Etsu Chemical Co., Ltd. (JP) 2005-03-02 EP disclosed