Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5701557 | 0.91 | LMNA (0.50) | LMNA | |
| SCHEMBL5701567 | 0.91 | LMNA (0.50) | LMNA | |
| SCHEMBL5701962 | 0.83 | LMNA (0.31) | LMNA | |
| SCHEMBL6269873 | 0.83 | LMNA (0.31) | LMNA | |
| SCHEMBL5701624 | 0.83 | LMNA (0.31) | LMNA | |
| SCHEMBL9470240 | 0.81 | — | — | |
| SCHEMBL19543795 | 0.80 | LMNA (0.35) | LMNA | |
| SCHEMBL6009511 | 0.80 | LMNA (0.50) | LMNA | |
| SCHEMBL20478196 | 0.80 | LMNA (0.50) | LMNA | |
| SCHEMBL20478198 | 0.80 | LMNA (0.50) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305293-A1 | Star silicone resins | O'LENICK KEVIN ANTHONY | 2010-12-02 | — | — | US | disclosed |
| US-20100008882-A1 | Silicone polyester resins in personal care applications | LAVAY CARTER | 2010-01-14 | — | — | US | disclosed |
| US-7632488-B1 | Crosslinked silicone polymers | SILTECH CORPORATION | 2009-12-15 | — | — | US | disclosed |
| US-20090297461-A1 | Personal Care and Dermatologic Compositions | PERLE ADAM | 2009-12-03 | — | — | US | disclosed |
| US-7407666-B2 | Linear silicone resins in personal care applications | SILTECH LLC (US) | 2008-08-05 | — | — | US | disclosed |
| US-20070196309-A1 | Linear silicone resins in personal care applications | CARDIAC PACEMAKERS, INC. (US) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090297461-A1 | Personal Care and Dermatologic Compositions | CUTA, DPM1, DSG1 | LMNA 233/4885 |
| US-20070196309-A1 | Linear silicone resins in personal care applications | HACD3, HACD2, MMS19 | LMNA 908/4885 |
| US-20100008882-A1 | Silicone polyester resins in personal care applications | PUF60, CUTA, FAM83A | LMNA 800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.