Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9715929 | 0.95 | ESR1 (0.35) | ESR1ESR2POLBCA4KDM4E | |
| SCHEMBL339880 | 0.88 | ESR1 (0.39) | ESR1ESR2CA4 | |
| SCHEMBL6546676 | 0.86 | ESR1 (0.38) | ESR1ESR2POLBCA4SMN1; SMN2 | |
| SCHEMBL6547559 | 0.86 | ESR1 (0.38) | ESR1ESR2POLBCA4SMN1; SMN2 | |
| SCHEMBL6547160 | 0.86 | ESR1 (0.38) | ESR1ESR2POLBCA4SMN1; SMN2 | |
| SCHEMBL18094270 | 0.85 | ESR1 (0.32) | ESR1ESR2POLBCA4 | |
| SCHEMBL18094254 | 0.84 | ESR1 (0.31) | ESR1ESR2POLB | |
| SCHEMBL645431 | 0.83 | POLB (0.38) | ESR1ESR2POLBCA4KDM4E | |
| SCHEMBL37986 | 0.83 | CA4 (0.41) | ESR1ESR2POLBCA4KDM4E | |
| SCHEMBL8437442 | 0.83 | ESR1 (0.33) | ESR1ESR2POLBCA4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1510520-B1 | Preparation of branched siloxane | SHINETSU CHEMICAL CO (JP) | 2006-07-26 | — | — | EP | disclosed |
| US-6943264-B2 | Preparation of branched siloxane | SHIN-ETSU CHEMICAL, CO., LTD. (JP) | 2005-09-13 | — | — | US | disclosed |
| US-20050049427-A1 | Preparation of branched siloxane | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2005-03-03 | — | — | US | disclosed |
| EP-1510520-A1 | Preparation of branched siloxane | Shin-Etsu Chemical Co., Ltd. (JP) | 2005-03-02 | — | — | EP | disclosed |