Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6547160 | 1.00 | ESR1 (0.38) | ESR1ESR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6546676 | 1.00 | ESR1 (0.38) | ESR1ESR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL339880 | 0.97 | ESR1 (0.39) | ESR1ESR2NR1H2NR1H3CA4 | |
| SCHEMBL12136745 | 0.89 | ESR1 (0.34) | ESR1ESR2 | |
| SCHEMBL2487952 | 0.89 | ESR1 (0.34) | ESR1ESR2 | |
| SCHEMBL26973343 | 0.87 | ESR1 (0.33) | ESR1ESR2 | |
| SCHEMBL5701692 | 0.86 | ESR1 (0.35) | ESR1ESR2SMN1; SMN2CA4POLB | |
| SCHEMBL9715929 | 0.86 | ESR1 (0.35) | ESR1ESR2SMN1; SMN2NR1H2NR1H3 | |
| SCHEMBL6547518 | 0.85 | ESR1 (0.36) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL18017234 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9416273-B1 | Curable composition and method for manufacturing the same | ETERNAL MATERIALS CO., LTD. (TW) | 2016-08-16 | — | — | US | disclosed |
| EP-0855418-B1 | Process for the preparation of high purity branched phenylsiloxane fluids | CLARIANT LSM ITALIA SPA (US) | 2004-01-21 | — | — | EP | disclosed |
| EP-0855418-A2 | High purity branched phenylsiloxane fluids | PCR, Inc. (US) | 1998-07-29 | — | — | EP | disclosed |
| US-5679822-A | High purity branched phenylsiloxane fluids | PCR, INC. (US) | 1997-10-21 | — | — | US | disclosed |