SCHEMBL9715929

SCHEMBL9715929

CO[Si](OC)(O[Si](C)(C)C)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
POLB P06746 1/20 0.34
CA4 P22748 1/20 0.33
NR1H2 P55055 1/20 0.32
NR1H3 Q13133 1/20 0.32
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 2/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5701692 0.95 ESR1 (0.35) ESR1ESR2POLBCA4KDM4E
SCHEMBL18094270 0.90 ESR1 (0.32) ESR1ESR2POLBCA4NR1H2
SCHEMBL339880 0.88 ESR1 (0.39) ESR1ESR2CA4NR1H2NR1H3
SCHEMBL645431 0.88 POLB (0.38) ESR1ESR2POLBCA4NR1H2
SCHEMBL18094254 0.88 ESR1 (0.31) ESR1ESR2POLB
SCHEMBL6546676 0.86 ESR1 (0.38) ESR1ESR2POLBCA4NR1H2
SCHEMBL6547559 0.86 ESR1 (0.38) ESR1ESR2POLBCA4NR1H2
SCHEMBL6547160 0.86 ESR1 (0.38) ESR1ESR2POLBCA4NR1H2
SCHEMBL14518576 0.84 ESR1 (0.34) ESR1ESR2POLBCA4NR1H2
SCHEMBL18094250 0.84 ESR1 (0.34) ESR1ESR2POLBCA4NR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0236044-B1 METHOD OF ADJUSTING PHYSICAL PROPERTIES IN SILICONE ELASTOMERIC SEALANT DOW CORNING CORPORATION (US) 1992-04-22 EP claimed
EP-0236044-A2 Method of adjusting physical properties in silicone elastomeric sealant DOW CORNING CORPORATION (US) 1987-09-09 EP claimed
US-4687829-A ALKOXY FUNCTIONAL GROUPS, CROSSLINKING, CHAIN EXTENSION, TITANIUM CATALYST, STORAGE DOW CORNING CORPORATION (US) 1987-08-18 US claimed
US-20230165126-A1 CURABLE SELF-ADHESIVE WAVELENGTH CONVERTING FILM AND LIGHT EMITTING DEVICE COMPRISING THE SAME OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2023-05-25 US disclosed
US-9994711-B2 Condensation-curable silicone composition and a semiconductor device SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-06-12 US disclosed
US-9862803-B2 Branched organopolysiloxane and a method for preparing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-01-09 US disclosed
US-9587075-B2 Addition-curable silicone composition and a semiconductor device SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-03-07 US disclosed
US-20160304673-A1 ADDITION-CURABLE SILICONE COMPOSITION AND A SEMICONDUCTOR DEVICE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-10-20 US disclosed
US-20160304675-A1 BRANCHED ORGANOPOLYSILOXANE AND A METHOD FOR PREPARING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-10-20 US disclosed
US-20160280959-A1 CONDENSATION-CURABLE SILICONE COMPOSITION AND A SEMICONDUCTOR DEVICE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-09-29 US disclosed
EP-0236044-B1 METHOD OF ADJUSTING PHYSICAL PROPERTIES IN SILICONE ELASTOMERIC SEALANT DOW CORNING CORPORATION (US) 1992-04-22 EP disclosed
EP-0236044-A2 Method of adjusting physical properties in silicone elastomeric sealant DOW CORNING CORPORATION (US) 1987-09-09 EP disclosed
US-4687829-A ALKOXY FUNCTIONAL GROUPS, CROSSLINKING, CHAIN EXTENSION, TITANIUM CATALYST, STORAGE DOW CORNING CORPORATION (US) 1987-08-18 US disclosed